Evidence map›Paper›PMID 20403559›Full record

ArticleOral and maxillofacial surgery clinics of North America2010

Salivary biosensors for screening trauma-related psychopathology.

Vivek Shetty, Masaki Yamaguchi

Abstract read
In one paragraph

Article in Oral and maxillofacial surgery clinics of North America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Biosensors in clinical chemistry - 2011 update.Clinica chimica acta; international journal of clinical chemistry · 2011
    Review
  10. Saliva sampling method affects performance of a salivary α-amylase biosensor.American journal of human biology : the official journal of the Human Biology Council
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vivek ShettySection of Oral and Maxillofacial Surgery, 23-009 UCLA School of Dentistry, University of California, 10833 Le Conte Avenue, Los Angeles, CA 90095-1668, USA. vshetty@ucla.edu <vshetty@ucla.edu>
Masaki Yamaguchi

Funding

Reducing the Disproportionate Burden of Orofacial InjuryR01DA016850 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHETTY, VIVEK · 2003 to 2007
$3.4M
Refinement and Validation of a Portable, Salivary Biosensor of Psychosocial StresU01DA023815 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHETTY, VIVEK · 2007 to 2010
$1.7M
NIDA NIH HHS 5R01DA016850NIDA NIH HHS 5UO1DA023815NIDA NIH HHS R01 DA016850NIDA NIH HHS U01 DA023815
6 · The paper itself

Abstract

After facial trauma, a distinct subset of patients goes on to develop mental health problems including recalcitrant psychopathology. Early identification of maladaptive stress reactions provides opportunities for initiating preemptive mental health interventions and hinges on the surgeon's ability to differentiate between transient distress and precursors of recalcitrant psychiatric sequelae. The comprehensive care of injured patients will benefit greatly from objective adjuncts and decision-making tools to complement the clinical evaluation. This article addresses meeting the need for practical, standardized, and reliable screening strategies through promising developments in the use of stress response biomarkers and biosensing technology. The systematic interrogation of differentially expressed stress response biomarkers in saliva now permits rapid assessment of the psychopathogical response to the stressor. Quantitative, point-of-use measurements of the traumatic stress response will greatly improve the nosology of posttraumatic stress disorders and help advance the screening, diagnosis, treatment, and prevention of mental health consequences of violence and trauma.

Indexed as

BiomarkersBiosensing TechniquesFacial InjuriesHumansHypothalamo-Hypophyseal SystemMass ScreeningMental DisordersPituitary-Adrenal SystemPoint-of-Care SystemsSalivaSignal Processing, Computer-AssistedStress Disorders, Post-TraumaticStress, PhysiologicalBiomarkers

Identifiers

PMID20403559
PMCPMC2858052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.