ArticleGenome biology2010
Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays.
Article in Genome biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Signals of Natural Selection across Regions of Low Recombination in Wild Populations of the Purple Sea Urchin, Strongylocentrotus purpuratus.Genome biology and evolution · 2026Article
- Selection Over Small and Large Spatial Scales in the Face of High Gene Flow.Molecular ecology · 2025Article
- Rare genetic variation and balanced polymorphisms are important for survival in global change conditions.Proceedings. Biological sciences · 2019Article
- Population structure, genetic connectivity, and adaptation in the Olympia oyster (Evolutionary applications · 2019Article
- Genome-wide signals of positive selection in strongylocentrotid sea urchins.BMC genomics · 2017Article
- Sensitivity of sea urchin fertilization to pH varies across a natural pH mosaic.Ecology and evolution · 2017Article
- Breaking RAD: an evaluation of the utility of restriction site-associated DNA sequencing for genome scans of adaptation.Molecular ecology resources · 2017Article
- AFSM sequencing approach: a simple and rapid method for genome-wide SNP and methylation site discovery and genetic mapping.Scientific reports · 2014Article
- The impact of gene expression variation on the robustness and evolvability of a developmental gene regulatory network.PLoS biology · 2013Article
- Going where traditional markers have not gone before: utility of and promise for RAD sequencing in marine invertebrate phylogeography and population genomics.Molecular ecology · 2013Article
- Evolutionary change during experimental ocean acidification.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Patterns of selection and polymorphism of innate immunity genes in bumblebees (Hymenoptera: Apidae).Genetica · 2012Article
- Genome-wide polymorphisms show unexpected targets of natural selection.Proceedings. Biological sciences · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-throughput genotype data can be used to identify genes important for local adaptation in wild populations, phenotypes in lab stocks, or disease-related traits in human medicine. Here we advance microarray-based genotyping for population genomics with Restriction Site Tiling Analysis. The approach simultaneously discovers polymorphisms and provides quantitative genotype data at 10,000s of loci. It is highly accurate and free from ascertainment bias. We apply the approach to uncover genomic differentiation in the purple sea urchin.
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Registered trials
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