ArticleBMC genomics2010
Transcriptome sequencing and development of an expression microarray platform for the domestic ferret.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Host Transcriptome Analysis of Ferret Tissues Following Henipavirus Infection.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Review
- Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains.PLoS neglected tropical diseases · 2018Article
- RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses (Frontiers in genetics · 2018Article
- A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels.Nature communications · 2016Article
- Ferret models of viral pathogenesis.Virology · 2015Review
- Isolation, characterization, and functional analysis of ferret lymphatic endothelial cells.Veterinary immunology and immunopathology · 2015Article
- Global and quantitative proteomic analysis of dogs infected by avian-like H3N2 canine influenza virus.Frontiers in microbiology · 2015Article
- TaqMan real time RT-PCR assays for detecting ferret innate and adaptive immune responses.Journal of virological methods · 2014Article
- The impact of "omic" and imaging technologies on assessing the host immune response to biodefence agents.Journal of immunology research · 2014Review
- Development of ferret as a human lung cancer model by injecting 4-(Nmethyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).Lung cancer (Amsterdam, Netherlands) · 2013Article
- Sequencing, annotation, and characterization of the influenza ferret infectome.Journal of virology · 2013Article
- Host gene expression signatures discriminate between ferrets infected with genetically similar H1N1 strains.PloS one · 2012Article
- De-novo transcriptome sequencing of a normalized cDNA pool from influenza infected ferrets.PloS one · 2012Article
- Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes).BMC genomics · 2011Article
- Animal models in carotenoids research and lung cancer prevention.Translational oncology · 2011Article
- Validation of assays to monitor immune responses in the Syrian golden hamster (Mesocricetus auratus).Journal of immunological methods · 2011Article
- The maternal and early embryonic transcriptome of the milkweed bug Oncopeltus fasciatus.BMC genomics · 2011Article
- Human brain evolution: harnessing the genomics (r)evolution to link genes, cognition, and behavior.Neuron · 2010Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe ferret (Mustela putorius furo) represents an attractive animal model for the study of respiratory diseases, including influenza. Despite its importance for biomedical research, the number of reagents for molecular and immunological analysis is restricted. We present here a parallel sequencing effort to produce an extensive EST (expressed sequence tags) dataset derived from a normalized ferret cDNA library made from mRNA from ferret blood, liver, lung, spleen and brain.
resultsWe produced more than 500000 sequence reads that were assembled into 16000 partial ferret genes. These genes were combined with the available ferret sequences in the GenBank to develop a ferret specific microarray platform. Using this array, we detected tissue specific expression patterns which were confirmed by quantitative real time PCR assays. We also present a set of 41 ferret genes with even transcription profiles across the tested tissues, indicating their usefulness as housekeeping genes.
conclusionThe tools developed in this study allow for functional genomic analysis and make further development of reagents for the ferret model possible.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.