ArticleBipolar disorders2010
Clinical characteristics of comorbid obsessive-compulsive disorder and bipolar disorder in children and adolescents.
Article in Bipolar disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Clinical impact of obsessive-compulsive disorder comorbidity in bipolar disorder: a systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Efficacy and safety of extended-release quetiapine fumarate in youth with bipolar depression: an 8 week, double-blind, placebo-controlled trial.Journal of child and adolescent psychopharmacology · 2014Trial
- Obsessive-Compulsive Disorder as an Epiphenomenon of Comorbid Bipolar Disorder? An Updated Systematic Review.Journal of clinical medicine · 2024Review
- Comorbidities in Youth with Bipolar Disorder: Clinical Features and Pharmacological Management.Current neuropharmacology · 2023Review
- Obsessive Compulsive Disorder and Bipolar Disorder Comorbidity: A Comparative Study.Iranian journal of psychiatry · 2022Article
- Borderline Personality Disorder "Discouraged Type": A Case Report.Medicina (Kaunas, Lithuania) · 2022Article
- How obsessive-compulsive and bipolar disorders meet each other? An integrative gene-based enrichment approach.Annals of general psychiatry · 2020Review
- Course and outcome of obsessive-compulsive disorder.Indian journal of psychiatry · 2019Review
- Electroconvulsive therapy for manic state with mixed and psychotic features in a teenager with bipolar disorder and comorbid episodic obsessive-compulsive disorder: a case report.Journal of medical case reports · 2017Article
- Obsessive Compulsive Inventory-Child Version (OCV-CI) to Evaluate Obsessive Compulsive Disorder in Children With Early Stages of Chronic Kidney Disease: A Case Control Study.Nephro-urology monthly · 2016Article
- Hoarding in Children and Adolescents with Obsessive-Compulsive Disorder.Journal of obsessive-compulsive and related disorders · 2014Article
- Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults.NeuroImage · 2013Article
- Phenomenological features and clinical impact of affective disorders in OCD: a focus on the bipolar disorder and OCD connection.Depression and anxiety · 2012Article
- A review of obsessive-compulsive disorder in children and adolescents.Dialogues in clinical neuroscience · 2011Review
- Obsessive-compulsive disorder comorbidity: clinical assessment and therapeutic implications.Frontiers in psychiatry · 2011Article
- Obsessive compulsive disorder with bipolar mood disorder: a rare comorbidity in India.Indian journal of psychological medicine · 2011Article
- Comorbidity Between Attention Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder Across the Lifespan: A Systematic and Critical Review.Harvard review of psychiatryReview
- How a common variant in the growth factor receptor gene, NTRK1, affects white matter.BioarchitectureArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo explore bidirectional comorbidity between bipolar disorder (BPD) and obsessive-compulsive disorder (OCD) in youth and to examine the symptom profile and clinical correlates of both disorders in the context of reciprocal comorbidity and ascertainment status.
methodsTwo samples of consecutively referred youth (ages 6-17 years) ascertained contemporaneously for respective studies of BPD and OCD were compared using clinical and scalar assessment and structured diagnostic interviews.
resultsA total of 21% (17/82) of the BPD subjects and 15% (19/125) of the OCD subjects met DSM-III-R diagnostic criteria for both disorders. In the presence of BPD, youth with OCD more frequently experienced hoarding/saving obsessions and compulsions along with a clinical profile of greater comorbidity, poorer global functioning, and higher rate of hospitalization that is characteristic of BPD. Multiple anxiety disorders (> or = 3), especially generalized anxiety disorder and social phobia, were present at a higher frequency when OCD and BPD were comorbid than otherwise. In subjects with comorbid OCD and BPD, the primary disorder of ascertainment was associated with an earlier onset and more severe impairment.
conclusionsAn unexpectedly high rate of comorbidity between BPD and OCD was observed in youth irrespective of primary ascertainment diagnosis. In youth with comorbid OCD and BPD, the clinical characteristics of each disorder run true and are analogues to their clinical presentation in youth without reciprocal comorbidity, with the exception of increased risk for obsessions and compulsions of hoarding/saving and comorbidity with other anxiety disorders.
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