Evidence map›Paper›PMID 20402519›Full record

ReviewChemical reviews2010

Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.

Yifat Miller, Buyong Ma, Ruth Nussinov

Abstract readReview
In one paragraph

Review in Chemical reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. amyloid-predict and LLPS-predict: Predicting phase separation propensities in the intrinsically disordered proteome.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Catalytic Amyloids: Turning Fibrils Into Biocatalysts.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. An N-terminal acidic β-sheet domain is responsible for the metal-accumulation properties of amyloid-β protofibrils: a molecular dynamics study.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Direct Observation of Seeded Conformational Conversion of hIAPPJournal of chemical information and modeling · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Molecular Insights into the Effect of Metals on Amyloid Aggregation.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  20. Review

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yifat MillerCenter for Cancer Research Nanobiology Program, NCI-Frederick, Frederick, Maryland 21702, USA.
Buyong Ma
Ruth Nussinov

Funding

Protein Structure, Stability, and Amyloid FormationZIABC010440 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI NUSSINOV, RUTH · 2009 to 2025
$11.8M
CCR NIH HHS HHSN261200800001CIntramural NIH HHSNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAmino Acid SequenceAmyloidAmyloid beta-PeptidesAnimalsBinding SitesChemical PhenomenaHumansHydrogen BondingHydrophobic and Hydrophilic InteractionsProtein ConformationProtein FoldingThermodynamicsAmyloidAmyloid beta-Peptides

Identifiers

PMID20402519
PMCPMC2920034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.