ArticleChromosoma1991
Chromosomal passengers: toward an integrated view of mitosis.
Article in Chromosoma, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
71 citing papers in PubMed, 201 citations in OpenAlex.
- Article
- Highway to hell-thy meiotic divisions: Chromosome passenger complex functions driven by microtubules: CPC interactions with both the chromosomes and microtubules are important for spindle assembly and function: CPC interactions with both the chromosomes and microtubules are important for spindle assembly and function.BioEssays : news and reviews in molecular, cellular and developmental biology · 2022Article
- APC/CJournal of cell science · 2020Article
- Cdc7 kinase stimulates Aurora B kinase in M-phase.Scientific reports · 2019Article
- First report on B chromosome content in a reptilian species: the case of Anolis carolinensis.Molecular genetics and genomics : MGG · 2019Article
- RCC2 promotes breast cancer progression through regulation of Wnt signaling and inducing EMT.Journal of Cancer · 2019Article
- The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.The Journal of biological chemistry · 2018Article
- HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry.The EMBO journal · 2018Article
- Chromosome passenger complex is required for the survival of cells with ring chromosomes in fission yeast.PloS one · 2018Article
- The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis.The Journal of biological chemistry · 2015Article
- The chromosomal passenger complex (CPC) as a key orchestrator of orderly mitotic exit and cytokinesis.Frontiers in cell and developmental biology · 2015Review
- RNA stimulates Aurora B kinase activity during mitosis.PloS one · 2014Article
- Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes.Journal of animal science and biotechnology · 2013Article
- The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.Nature reviews. Molecular cell biology · 2012Review
- The chromosomal passenger complex activates Polo kinase at centromeres.PLoS biology · 2012Article
- Aurora B kinase activation requires survivin priming phosphorylation by PLK1.Journal of molecular cell biology · 2011Article
- Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis.The Journal of biological chemistry · 2010Article
- Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset.Current biology : CB · 2010Article
- The life and miracles of kinetochores.The EMBO journal · 2009Review
- PRC1 cooperates with CLASP1 to organize central spindle plasticity in mitosis.The Journal of biological chemistry · 2009Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The major events of mitosis have traditionally been considered to represent two distinct pathways and have been studied by two separate groups of workers. The chromosomal events (chromosome condensation and sister chromatid disjunction) have been the principal focus for one group, while the cytoskeletal events (nuclear envelope breakdown, chromosomal movements, cytokinesis) have been the focus for the other. This historical division is epitomized by the view of many cell biologists, which was aptly caught by Mazia's comparison of the role of the chromosome arms in mitosis to that of "the corpse at the funeral" which "provide a reason for the proceedings but do not take an active part in them" (Mazia 1961). More recent studies have demonstrated that the role of the chromosomes in mitotic movements is somewhat more active than this. That the kinetochore may play an important role in chromosome movements has long been suspected (see early references in Mazia 1961) but was only proven rather recently (Brinkley et al. 1988; Gorbsky et al. 1987; Nicklas 1989). This has led to a burst of recent interest in all aspects of kinetochore structure and function. Our studies have led us to ask whether chromosomes may play an even more extensive role in the events of mitosis. We suggest here that in addition to their active role in movements, the chromosome may make important structural contributions to the anaphase spindle and cleavage furrow, which are normally thought of as "cytoskeletal" functions. These structural contributions may be made by members of a new class of "chromosomal passenger" proteins that use the chromosomes as a means of conveyance so that they are correctly positioned at the metaphase plate to carry out their nonchromosomal functions during anaphase and the subsequent mitotic events.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.