ArticleClinical research in cardiology : official journal of the German Cardiac Society2010
Regional variation of mortality from ischemic heart disease in Germany from 1998 to 2007.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Smoking restrictions and hospitalization for acute coronary events in Germany.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Article
- Article
- Autonomic regulation during mild therapeutic hypothermia in cardiopulmonary resuscitated patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Article
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Authors and funding
6 authors.
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Abstract
backgroundPrevious research revealed substantial differences in mortality due to ischemic heart disease (IHD) between the 16 German states. As variation may also be present within these states, analyses with higher geographical resolution are necessary to characterize changes in the magnitude of variation over time.
aimTo describe regional differences of IHD mortality in Germany over a period of 10 years (1998 and 2007) on a county level and to investigate whether variation in mortality can be explained by region.
methodsData on deaths due to IHD (ICD 10 I20-I25) and the number of inhabitants were obtained from the State Offices for Statistics to calculate age-standardized rates. Poisson regression models with and without random effects and measures of absolute variability (standard deviation) and relative variability (coefficient of variation) were used to analyze mortality due to IHD.
resultsRegional differences in IHD mortality were observed (p < 0.001) with the highest burden in the northeast and the lowest in the southwest. From 1998 to 2007, age-standardized mortality rates due to IHD decreased by >35% in men and women (p < 0.001). While measure of absolute variability between German regions also decreased by >35% (p < 0.001), measures of relative geographical differences did not change in men (-2.5%, p = 0.618) and decreased only slightly in women (-10.2%, p = 0.044).
conclusionThere is a marked regional variation of IHD mortality in Germany. The relative variability changed little during the last 10 years and provides a unique chance to characterize the impact of important IHD risk factors on the population level and improve preventive strategies.
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