ArticleLab on a chip2010
Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications.
Article in Lab on a chip, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
150 citing papers in PubMed.
- Lensless Quantitative Phase Imaging with Bayer-Filtered Color Sensors Under Sequential RGB-LED Illumination.Journal of imaging · 2026Article
- Article
- Automated HER2 Scoring with Uncertainty Quantification Using Lensfree Holography and Deep Learning.BME frontiers · 2026Article
- OpenLM: an open-source pixel super-resolution platform for lens-free microscopy with applications in bacterial growth monitoring and deep learning-based bacterial detection.Lab on a chip · 2025Article
- Calibration of Digital Holographic Camera for Bubble Gas Volumetric Flux Measurements.Sensors (Basel, Switzerland) · 2025Article
- Multi-Channel Cellytics for Rapid and Cost-Effective Monitoring of Leukocyte Activation.Biosensors · 2025Article
- Advances in Portable Optical Microscopy Using Cloud Technologies and Artificial Intelligence for Medical Applications.Sensors (Basel, Switzerland) · 2024Review
- Lens-free on-chip 3D microscopy based on wavelength-scanning Fourier ptychographic diffraction tomography.Light, science & applications · 2024Article
- A customizable digital holographic microscope.HardwareX · 2024Article
- Long-term imaging of three-dimensional hyphal development using the ePetri dish.Biomedical optics express · 2024Article
- Quantitative phase imaging based on holography: trends and new perspectives.Light, science & applications · 2024Review
- Off-axis digital lensless holographic microscopy based on spatially multiplexed interferometry.Journal of biomedical optics · 2024Article
- All-optical complex field imaging using diffractive processors.Light, science & applications · 2024Article
- Spatially-coded Fourier ptychography: flexible and detachable coded thin films for quantitative phase imaging with uniform phase transfer characteristics.Advanced optical materials · 2024Article
- Chromatic Aberration Correction in Harmonic Diffractive Lenses Based on Compressed Sensing Encoding Imaging.Sensors (Basel, Switzerland) · 2024Article
- Multi-scale fractal Fourier Ptychographic microscopy to assess the dose-dependent impact of copper pollution on living diatoms.Scientific reports · 2024Article
- Improved resolution in fiber bundle inline holographic microscopy using multiple illumination sources.Biomedical optics express · 2024Article
- Ptychographic lens-less birefringence microscopy using a mask-modulated polarization image sensor.Scientific reports · 2023Article
- Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning.Nature biomedical engineering · 2023Article
- Spatial- and Fourier-domain ptychography for high-throughput bio-imaging.Nature protocols · 2023Review
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Despite the rapid progress in optical imaging, most of the advanced microscopy modalities still require complex and costly set-ups that unfortunately limit their use beyond well equipped laboratories. In the meantime, microscopy in resource-limited settings has requirements significantly different from those encountered in advanced laboratories, and such imaging devices should be cost-effective, compact, light-weight and appropriately accurate and simple to be usable by minimally trained personnel. Furthermore, these portable microscopes should ideally be digitally integrated as part of a telemedicine network that connects various mobile health-care providers to a central laboratory or hospital. Toward this end, here we demonstrate a lensless on-chip microscope weighing approximately 46 grams with dimensions smaller than 4.2 cm x 4.2 cm x 5.8 cm that achieves sub-cellular resolution over a large field of view of approximately 24 mm(2). This compact and light-weight microscope is based on digital in-line holography and does not need any lenses, bulky optical/mechanical components or coherent sources such as lasers. Instead, it utilizes a simple light-emitting-diode (LED) and a compact opto-electronic sensor-array to record lensless holograms of the objects, which then permits rapid digital reconstruction of regular transmission or differential interference contrast (DIC) images of the objects. Because this lensless incoherent holographic microscope has orders-of-magnitude improved light collection efficiency and is very robust to mechanical misalignments it may offer a cost-effective tool especially for telemedicine applications involving various global health problems in resource limited settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.