ArticleThe Journal of pediatrics2010
Use of screening dried blood spots for estimation of prevalence, risk factors, and birth outcomes of congenital cytomegalovirus infection.
Article in The Journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Congenital Cytomegalovirus Infection Burden and Epidemiologic Risk Factors in Countries With Universal Screening: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- Congenital Cytomegalovirus Among Newborns in Neonatal Intensive Care Units, United States, 2010-2020.Birth defects research · 2026Article
- Congenital CMV and Hearing Loss-How Does it Happen and How to Prevent it.Reviews in medical virology · 2026Review
- Review
- Disparities in Congenital Cytomegalovirus (cCMV) Postpartum Newborn Screening Research Participation.Journal of racial and ethnic health disparities · 2025Article
- Targeted Screening with the Use of Clinical Risk Factors for Detecting Congenital Cytomegalovirus Infection in Newborns: A Prospective Multicenter Cohort Study.Microorganisms · 2025Article
- Autism Spectrum Disorder Diagnoses and Congenital Cytomegalovirus.Pediatrics · 2024Article
- Estimates of congenital cytomegalovirus-attributable infant mortality in high-income countries: A review.Reviews in medical virology · 2024Review
- Early childhood outcomes of NICU graduates with cytomegalovirus infection in California.Birth defects research · 2023Article
- Maternal CMV seroprevalence rate in early gestation and congenital cytomegalovirus infection in a Chinese population.Emerging microbes & infections · 2021Observational
- Clinical Diagnostic Testing for Human Cytomegalovirus Infections.The Journal of infectious diseases · 2020Review
- Congenital Cytomegalovirus Infection.The Journal of infectious diseases · 2020Review
- Viral Loads in Congenital Cytomegalovirus Infection From a Highly Immune Population.Journal of the Pediatric Infectious Diseases Society · 2018Article
- CMV on surfaces in homes with young children: results of PCR and viral culture testing.BMC infectious diseases · 2018Article
- Detection of congenital cytomegalovirus in newborns using nucleic acid amplification techniques and its public health implications.Virologica Sinica · 2017Review
- Cohort study on maternal cytomegalovirus seroprevalence and prevalence and clinical manifestations of congenital infection in China.Medicine · 2017Article
- Congenital Cytomegalovirus Infection: Maternal-Child HLA-C, HLA-E, and HLA-G Affect Clinical Outcome.Frontiers in immunology · 2017Article
- Evaluation of DNA extraction methods for the detection of Cytomegalovirus in dried blood spots.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2015Article
- Repeated measures study of weekly and daily cytomegalovirus shedding patterns in saliva and urine of healthy cytomegalovirus-seropositive children.BMC infectious diseases · 2014Article
- Cross-sectional study of cytomegalovirus shedding and immunological markers among seropositive children and their mothers.BMC infectious diseases · 2014Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the birth prevalence of cytomegalovirus (CMV) in a population-based sample of newborns by use of dried blood spots compared with previous studies that used established detection methods, and to evaluate risk factors and birth outcomes for congenital CMV infection. STUDY
designA total of 3972 newborn dried blood spots collected for the California Newborn Screening Program were tested for presence of CMV DNA. Demographic and pregnancy data were obtained from linked newborn screening and live-birth records.
resultsCMV prevalence among newborns by maternal race and ethnicity was 0.9% for blacks, 0.8% for Hispanics, 0.6% for whites, and 0.6% for Asians. Among Hispanics (n = 2053), infants who were infected had younger mothers (23 vs 26 years, P = .03), and prevalence was higher for children with no father information provided (2.6% vs 0.6%, P = .03). Overall CMV infection was associated with low birth weight (prevalence ratios [95% CI]: 3.4 [1.4-8.5]) and preterm birth (2.7 [1.4-5.1]). CMV viral loads were inversely related to birth weight and gestational age (both P = .03).
conclusionsCMV prevalence measured with dried blood spots was similar to reports using standard viral culture methods. Dried blood spots may be suitable for detection of CMV infection in newborns and warrant further evaluation. Congenital CMV infection may contribute to low birth weight and preterm birth.
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