ArticleBrain research reviews2011
Biocytin-labelling and its impact on late 20th century studies of cortical circuitry.
Article in Brain research reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Computational Generation of Long-range Axonal Morphologies.Neuroinformatics · 2025Article
- Millimetric scale two-photon Bessel-Gauss beam light sheet microscopy with three-axis isotropic resolution using an axicon lens.Neurophotonics · 2023Article
- [Communication sound recognition and response modification in the secondary auditory cortex of female mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Minimizing shrinkage of acute brain slices using metal spacers during histological embedding.Brain structure & function · 2020Article
- Statistical analysis and data mining of digital reconstructions of dendritic morphologies.Frontiers in neuroanatomy · 2014Article
- A comparison of manual neuronal reconstruction from biocytin histology or 2-photon imaging: morphometry and computer modeling.Frontiers in neuroanatomy · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In recognition of the impact that a powerful new anatomical tool, such as the Golgi method, can have, this essay highlights the enormous influence that biocytin-filling has had on modern neuroscience. This method has allowed neurones that have been recorded intracellularly, 'whole-cell' or juxta-cellularly, to be identified anatomically, forming a vital link between functional and structural studies. It has been applied throughout the nervous system and has become a fundamental component of our technical armoury. A comprehensive survey of the applications to which the biocytin-filling approach has been put, would fill a large volume. This essay therefore focuses on one area, neocortical microcircuitry and the ways in which combining physiology and anatomy have revealed rules that help us explain its previously indecipherable variability and complexity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.