Evidence map›Paper›PMID 20399632›Full record

ReviewCurrent opinion in cell biology2010

The ciliary membrane.

Rajat Rohatgi, William J Snell

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 174 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. G Protein-Coupled Receptor Signal Intersection at the Primary Cilium.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Midbody remnant regulates the formation of primary cilia and their roles in tumor growth.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Initial ciliary assembly inMolecular biology of the cell · 2023
    Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rajat RohatgiDepartment of Medicine, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA. rrohatgi@stanford.edu
William J Snell
Stanford University · US

Funding

CELL SURFACE RECOGNITION AND CELL INTERACTIONSR01GM025661 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI SNELL, WILLIAM J · 1985 to 2017
$5.9M
Biochemical Mechanisms of Hedgehog SignalingR00CA129174 · NCI · STANFORD UNIVERSITY · PI ROHATGI, RAJAT · 2009 to 2011
$1.0M
NCI NIH HHS R00 CA129174NIGMS NIH HHS GM 25661NIGMS NIH HHS R01 GM025661
6 · The paper itself

Abstract

Cilia and flagella are important organizing centers for signaling in both development and disease. A key to their function is a poorly characterized barrier at their base that allows the protein and lipid composition of the ciliary membrane to be distinct from that of the plasma membrane. We review current models of ciliary membrane biogenesis, highlighting several structures, including the ciliary necklace and ciliary pocket, that appear during biogenesis and that likely contribute to the barrier. The regulated movement of membrane proteins and lipids across this barrier is central to the sensory function of these organelles.

Indexed as

AnimalsCiliaHumansIntracellular MembranesLipid MetabolismMembrane ProteinsProtein TransportSignal TransductionMembrane Proteins

Identifiers

PMID20399632
PMCPMC2910237
OpenAlexW2080273070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.