Evidence map›Paper›PMID 20399610›Full record

ArticleSchizophrenia research2010

Potential stigma associated with inclusion of the psychosis risk syndrome in the DSM-V: an empirical question.

Lawrence H Yang, Ahtoy J Wonpat-Borja, Mark G Opler, Cheryl M Corcoran

Abstract read
In one paragraph

Article in Schizophrenia research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 155 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Predicting risk of psychosis in primary care: a qualitative study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Ethical challenges in contemporary psychiatry: an overview and an appraisal of possible strategies and research needs.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. A Narrative Review of Alzheimer's Disease Stigma.Journal of Alzheimer's disease : JAD · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lawrence H YangColumbia University, Department of Epidemiology, School of Public Health, 722 West 168th Street, New York, NY 10032, USA. lhy2001@columbia.edu
Ahtoy J Wonpat-Borja
Mark G Opler
Cheryl M Corcoran
Columbia University · USNew York University · US

Funding

Schizophrenia risk to onset: Neurobiology and preventionK23MH066279 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CORCORAN, CHERYL MARY · 2004 to 2008
$884k
Expressed Emotion and Stigma among Chinese-Americans with SchizophreniaK01MH073034 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YANG, LAWRENCE H · 2005 to 2009
$785k
NIMH NIH HHS K01 MH073034NIMH NIH HHS K01-MH73034-01NIMH NIH HHS K23-MH066279-01A2
6 · The paper itself

Abstract

While the "clinical high-risk state" for psychosis has demonstrated good reliability and fair predictive validity for psychotic disorders, over 50% of identified subjects do not progress to psychosis. Despite the benefits that early detection and treatment might offer, debate concerning the official inclusion of a "psychosis risk syndrome" in the upcoming DSM-V frequently involves concerns about the impact of stigma on patients, families and institutions. We add to this debate by providing an analysis of the theoretical and empirical stigma literature to evaluate the potential effects of stigma associated with the psychosis risk syndrome. Theorists' conceptualizations of how stigma exerts its negative effects emphasize internalization of pejorative societal stereotypes ('self-stigma'), negative emotional reactions, harmful behavioral coping strategies, and structural discrimination as key mechanisms. Studies assessing the comparative effects of symptomatic behavior when compared with a psychiatric diagnosis label in predicting rejecting social attitudes indicate that treating symptomatic behaviors is likely to diminish overall stigma. However, any publically held 'preexisting conceptions' about what a psychosis risk syndrome means are still likely to exert negative effects. Additionally, particular features of this syndrome--that it occurs during adolescence when identity formation may be in flux--may also shape manifestations of stigma. Utilizing other well-established 'at-risk' conditions (e.g., genetic susceptibility) to model potential discrimination for this syndrome, we suggest that future discrimination is likely to occur in insurance and family domains. We conclude by proposing stigma measurement strategies, including recommending that field trials prior to DSM-V adopt systematic measures to assess any stigma that this psychosis risk syndrome might confer via future community use.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersHumansMental DisordersPsychiatric Status Rating ScalesPsychotic DisordersRisk Factors

Identifiers

PMID20399610
PMCPMC2921374
OpenAlexW2165887956

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.