Evidence map›Paper›PMID 20397955›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2010

Tuberculosis as part of the natural history of HIV infection in developing countries.

Gabriel Chamie, Annie Luetkemeyer, Edwin Charlebois, Diane V Havlir

Abstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Priorities for tuberculosis research: a systematic review.The Lancet. Infectious diseases · 2010
    Pooled it
  2. Tuberculosis challenges: Resistance, co-infection, diagnosis, and treatment.European journal of microbiology & immunology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriel ChamieHIV/AIDS Division, San Francisco General Hospital, University of California, San Francisco, USA. gabriel.chamie@ucsf.edu
Annie Luetkemeyer
Edwin Charlebois
Diane V Havlir

Funding

San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
Therapeutic Strategies for HIV DiseaseK24AI051982 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V · 2002 to 2012
$1.3M
Molecular Epidemiology and Geospatial Analysis of TB Transmission in UgandaK23AI095034 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAMIE, GABRIEL · 2011 to 2015
$637k
NIAID NIH HHS K23 AI095034NIAID NIH HHS K24 AI051982NIAID NIH HHS UM1 AI069496NIMH NIH HHS T32 MH019105NIMH NIH HHS T32 MH-19105-21PHS HHS K-24 A151982
6 · The paper itself

Abstract

An enhanced, refocused research agenda is critical to reducing the burden of tuberculosis (TB) in the human immunodeficiency virus (HIV) epidemic in developing countries. TB threatens HIV-infected patients before and after initiation of antiretroviral therapy, is difficult to diagnose, is rapidly fatal when it is drug resistant, and is being spread in clinics and hospitals. Research priorities include improved and point-of-care TB diagnostics; TB treatment and prevention during HIV infection, drug-resistant TB, and childhood TB; and optimization of TB and HIV program integration. With new TB diagnostics and drugs reaching approval, research must focus on effectively deploying these advancements. Research must include evaluations of individual, household, health care, and community approaches. Studies must apply implementation science to determine how to increase and adapt effective interventions to reduce TB burden in the context of HIV infection. Investment in this research will improve the lives of persons infected with HIV and contribute to efforts to reduce the global TB burden.

Indexed as

AIDS-Related Opportunistic InfectionsBiomedical ResearchCommunicable Disease ControlDeveloping CountriesHIV InfectionsHumansTuberculosis

Identifiers

PMID20397955
PMCPMC3032796

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.