Evidence map›Paper›PMID 20397928›Full record

ReviewStem cells and development2010

Alternative sources of pluripotent stem cells: ethical and scientific issues revisited.

Maureen L Condic, Mahendra Rao

Abstract readReview
In one paragraph

Review in Stem cells and development, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Stem cell therapy use in patients with dementia: a systematic review.International journal of emergency medicine · 2025
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Role of heat shock proteins in stem cell behavior.Progress in molecular biology and translational science · 2012
    Review
  8. Keeping things simple.Nature methods · 2011
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maureen L CondicDepartment of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132-3401, USA. mlcondic@neuro.utah.edu
Mahendra Rao

Funding

Specification and development of sensory neuronsR01NS048382 · NINDS · UNIVERSITY OF UTAH · PI CONDIC, MAUREEN L · 2004 to 2009
$1.5M
NINDS NIH HHS R01 NS048382
6 · The paper itself

Abstract

Stem cell researchers in the United States continue to face an uncertain future, because of the changing federal guidelines governing this research, the restrictive patent situation surrounding the generation of new human embryonic stem cell lines, and the ethical divide over the use of embryos for research. In this commentary, we describe how recent advances in the derivation of induced pluripotent stem cells and the isolation of germ-line-derived pluripotent stem cells resolve a number of these uncertainties. The availability of patient-matched, pluripotent stem cells that can be obtained by ethically acceptable means provides important advantages for stem cell researchers, by both avoiding protracted ethical debates and giving U.S. researchers full access to federal funding. Thus, ethically uncompromised stem cells, such as those derived by direct reprogramming or from germ-cell precursors, are likely to yield important advances in stem cell research and move the field rapidly toward clinical applications.

Indexed as

AnimalsEmbryonic Stem CellsGerm CellsHumansInduced Pluripotent Stem CellsPluripotent Stem CellsStem Cell Research

Identifiers

PMID20397928
PMCPMC3128309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.