Evidence map›Paper›PMID 20397259›Full record

ReviewWorld journal of gastroenterology2010

Chemokines and hepatocellular carcinoma.

Fan Huang, Xiao-Ping Geng

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. EMT and Inflammation: Crossroads in HCC.Journal of gastrointestinal cancer · 2023
    Review
  6. Review
  7. Article
  8. Chemokines in Primary Liver Cancer.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Review
  11. Investigation of Anti-Liver Cancer Activity of the Herbal Drug FDY003 Using Network Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  12. Article
  13. Review
  14. The CCL20-CCR6 Axis in Cancer Progression.International journal of molecular sciences · 2020
    Review
  15. Article
  16. The Diagnostic Value of Chemokine/Chemokine Receptor Pairs in Hepatocellular Carcinoma and Colorectal Liver Metastasis.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2019
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fan HuangDepartment of Hepatobiliary Surgery of the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China.
Xiao-Ping Geng
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokines play a paramount role in tumor progression. In hepatocellular carcinoma (HCC) progression, chemokines and their receptors play an intricate role. Currently, chemokines and their receptors such as the CXCL12-CXCR4 axis, CX3CL1-CX3CR1 axis and the CCL20-CCR6 axis have received much research attention. Although a large number of studies show that these axes are strongly associated with HCC, the exact mechanism by which these axes promote the growth and progression of HCC remains unknown. In this paper, several chemokines and their receptor interactions in HCC progression, growth and metastasis and immune response to HCC are reviewed.

Indexed as

Gene Expression Regulation, NeoplasticAnimalsAntineoplastic AgentsCarcinoma, HepatocellularChemokine CCL20Chemokine CXCL12ChemokinesDisease ProgressionHumansImmune SystemLiver NeoplasmsModels, BiologicalNeoplasm MetastasisReceptors, CCR6Receptors, CXCR4Antineoplastic AgentsCCL20 protein, humanCCR6 protein, humanChemokine CCL20Chemokine CXCL12ChemokinesCXCL12 protein, humanCXCR4 protein, humanReceptors, CCR6Receptors, CXCR4ChemokinesHepatocellular carcinoma

Identifiers

PMID20397259
PMCPMC2856822
OpenAlexW1965397916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.