Evidence map›Paper›PMID 20397175›Full record

ArticleAngewandte Chemie (International ed. in English)2010

Multidimensional structure-activity relationship of a protein in its aggregated states.

Lei Wang, David Schubert, Michael R Sawaya, David Eisenberg, Roland Riek

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
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  11. Article
  12. Two distinct aggregation pathways in transthyretin misfolding and amyloid formation.Biochimica et biophysica acta. Proteins and proteomics · 2019
    Article
  13. Article
  14. The Three-Dimensional Structures of Amyloids.Cold Spring Harbor perspectives in biology · 2017
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lei WangLaboratorium für Physikalische Chemie, ETH Zürich, 8093 Zürich, Switzerland.
David Schubert
Michael R Sawaya
David Eisenberg
Roland Riek

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine TriphosphateBenzothiazolesCell SurvivalDNAProteinsProtein Structure, SecondaryStructure-Activity RelationshipThiazolesAdenosine TriphosphateBenzothiazolesDNAProteinsThiazolesthioflavin T

Identifiers

PMID20397175
PMCPMC3004770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.