ArticleAngewandte Chemie (International ed. in English)2010
Structure-activity relationships through sequencing (StARTS) defines optimal and suboptimal RNA motif targets for small molecules.
Article in Angewandte Chemie (International ed. in English), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Small molecule approaches to targeting RNA.Nature reviews. Chemistry · 2024Review
- Contemporary Progress and Opportunities in RNA-Targeted Drug Discovery.ACS medicinal chemistry letters · 2023Review
- Expanding the DNA-encoded library toolbox: identifying small molecules targeting RNA.Nucleic acids research · 2022Article
- Noncoding RNAs in Glioblastoma: Emerging Biological Concepts and Potential Therapeutic Implications.Cancers · 2021Review
- Targeting RNA structures in diseases with small molecules.Essays in biochemistry · 2020Review
- A Loop-Based and AGO-Incorporated Virtual Screening Model Targeting AGO-Mediated miRNA-mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Small molecule targeting of RNA structures in neurological disorders.Annals of the New York Academy of Sciences · 2020Review
- Review
- Unveiling the druggable RNA targets and small molecule therapeutics.Bioorganic & medicinal chemistry · 2019Review
- Targeting RNA with Small Molecules To Capture Opportunities at the Intersection of Chemistry, Biology, and Medicine.Journal of the American Chemical Society · 2019Article
- RNA Structural Differentiation: Opportunities with Pattern Recognition.Biochemistry · 2019Review
- Drugging the RNA World.Cold Spring Harbor perspectives in biology · 2018Review
- Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.Chemical reviews · 2018Review
- Defining RNA-Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA.ACS central science · 2017Article
- Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence.Accounts of chemical research · 2016Article
- The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Cell chemical biology · 2016Review
- Microarray-based technologies for the discovery of selective, RNA-binding molecules.Methods (San Diego, Calif.) · 2016Review
- Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs.ACS chemical biology · 2016Article
- Small molecules targeting microRNA for cancer therapy: Promises and obstacles.Journal of controlled release : official journal of the Controlled Release Society · 2015Review
- Structure based approaches for targeting non-coding RNAs with small molecules.Current opinion in structural biology · 2015Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.