ReviewCerebellum (London, England)2010
Rebound discharge in deep cerebellar nuclear neurons in vitro.
Review in Cerebellum (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 53 citations in OpenAlex.
- Cerebellar acceleration of learning in an evidence-accumulation task.Cell reports · 2026Article
- Isolation, total synthesis, and biological evaluation of dearomatized isoprenylated acylphloroglucinols from Hypericum przewalskii.Natural products and bioprospecting · 2026Article
- The cerebellum shapes motions by encoding motor frequencies with precision and cross-individual uniformity.Nature biomedical engineering · 2025Article
- Cerebellar stimulation prevents Levodopa-induced dyskinesia in mice and normalizes activity in a motor network.Nature communications · 2022Article
- Structural and functional brain changes in X-linked Charcot-Marie-Tooth disease: insights from a multimodal neuroimaging study.Neuroradiology · 2022Article
- Differential Coding Strategies in Glutamatergic and GABAergic Neurons in the Medial Cerebellar Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Cerebellar Cortex 4-12 Hz Oscillations and Unit Phase Relation in the Awake Rat.Frontiers in systems neuroscience · 2020Article
- The Cerebro-Cerebellum as a Locus of Forward Model: A Review.Frontiers in systems neuroscience · 2020Article
- Physiological and Morphological Principles Underpinning Recruitment of the Cerebellar Reserve.CNS & neurological disorders drug targets · 2018Review
- In vivo analysis of synaptic activity in cerebellar nuclei neurons unravels the efficacy of excitatory inputs.The Journal of physiology · 2017Article
- Article
- Determinants of rebound burst responses in rat cerebellar nuclear neurons to physiological stimuli.The Journal of physiology · 2016Article
- Characterization of Rebound Depolarization in Neurons of the Rat Medial Geniculate Body In Vitro.Neuroscience bulletin · 2016Article
- Whole-Cell Properties of Cerebellar Nuclei Neurons In Vivo.PloS one · 2016Article
- The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential.Pharmacological reviews · 2015Review
- Bidirectional modulation of deep cerebellar nuclear cells revealed by optogenetic manipulation of inhibitory inputs from Purkinje cells.Neuroscience · 2014Article
- Releasing dentate nucleus cells from Purkinje cell inhibition generates output from the cerebrocerebellum.PloS one · 2014Article
- Signal processing by T-type calcium channel interactions in the cerebellum.Frontiers in cellular neuroscience · 2013Review
- Burst generation mediated by cholinergic input in terminal nerve-gonadotrophin releasing hormone neurones of the goldfish.The Journal of physiology · 2013Article
- Modeling the generation of output by the cerebellar nuclei.Neural networks : the official journal of the International Neural Network Society · 2013Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Neurons of the deep cerebellar nuclei (DCN) play a critical role in defining the output of cerebellum in the course of encoding Purkinje cell inhibitory inputs. The earliest work performed with in vitro preparations established that DCN cells have the capacity to translate membrane hyperpolarizations into a rebound increase in firing frequency. The primary means of distinguishing between DCN neurons has been according to cell size and transmitter phenotype, but in some cases, differences in the firing properties of DCN cells maintained in vitro have been reported. In particular, it was shown that large diameter cells in the rat DCN exhibit two phenotypes of rebound discharge in vitro that may eventually help define their functional roles in cerebellar output. A transient burst and weak burst phenotype can be distinguished based on the frequency and pattern of rebound discharge immediately following a hyperpolarizing stimulus. Work to date indicates that the difference in excitability arises from at least the degree of activation of T-type Ca(2+) current during the immediate phase of rebound firing and Ca(2+)-dependent K(+) channels that underlie afterhyperpolarizations. Both phenotypes can be detected following stimulation of Purkinje cell inhibitory inputs under conditions that preserve resting membrane potential and natural ionic gradients. In this paper, we review the evidence supporting the existence of different rebound phenotypes in DCN cells and the ion channel expression patterns that underlie their generation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.