ArticleJournal of materials science. Materials in medicine2010
Biocorrosion properties and blood and cell compatibility of pure iron as a biodegradable biomaterial.
Article in Journal of materials science. Materials in medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 151 citations in OpenAlex.
- Synthesis of Iron(II,III) Oxide-Titanium Core-Shell Particles via Magnetron Sputtering for Magnetoactive Elastomers.ACS omega · 2026Article
- Biodegradable Metal-Based Stents: Advances, Challenges, and Prospects.Journal of functional biomaterials · 2025Review
- Study of the effect of magnetic fields on static degradation of Fe and Fe-12Mn-1.2C in balanced salts modified Hanks' solution.Bioactive materials · 2024Article
- Research status and prospects of biodegradable magnesium-based metal guided bone regeneration membranes.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2024Review
- Article
- Influence of Dynamic Strain Sweep on the Degradation Behavior of FeMnSi-Ag Shape Memory Alloys.Journal of functional biomaterials · 2023Article
- Biomaterials as Implants in the Orthopedic Field for Regenerative Medicine: Metal versus Synthetic Polymers.Polymers · 2023Review
- In Vitro Degradation and Photoactivated Antibacterial Activity of a Hemin-CaP Microsphere-Loaded Coating on Pure Magnesium.Journal of functional biomaterials · 2022Article
- Progress in manufacturing and processing of degradable Fe-based implants: a review.Progress in biomaterials · 2022Review
- Biodegradable Iron and Porous Iron: Mechanical Properties, Degradation Behaviour, Manufacturing Routes and Biomedical Applications.Journal of functional biomaterials · 2022Review
- A Critical Review of Additive Manufacturing Techniques and Associated Biomaterials Used in Bone Tissue Engineering.Polymers · 2022Review
- Interaction of thin polyethyleneimine layer with the iron surface and its effect on the electrochemical behavior.Scientific reports · 2022Article
- Biodegradation behaviour of Fe-based alloys in Hanks' Balanced Salt Solutions: Part I. material characterisation and corrosion testing.Bioactive materials · 2022Article
- Biodegradation behaviour of Fe-based alloys in Hanks' Balanced Salt Solutions: Part II. The evolution of local pH and dissolved oxygen concentration at metal interface.Bioactive materials · 2022Article
- The application of inferior vena cava filters in orthopaedics and current research advances.Frontiers in bioengineering and biotechnology · 2022Review
- Corrosion Behavior of Zn, Fe and Fe-Zn Powder Materials Prepared via Uniaxial Compression.Materials (Basel, Switzerland) · 2021Article
- Local and systemic inflammation after implantation of a novel iron based porous degradable bone replacement material in sheep model.Scientific reports · 2021Article
- Bioresorbable hydrogels prepared by photo-initiated crosslinking of diacrylated PTMC-PEG-PTMC triblock copolymers as potential carrier of antitumor drugs.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- In Vitro Corrosion Behavior of Biodegradable Iron Foams with Polymeric Coating.Materials (Basel, Switzerland) · 2020Article
- Are Fe-Based Stenting Materials Biocompatible? A Critical Review ofJournal of functional biomaterials · 2019Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biocorrosion properties and blood- and cell compatibility of pure iron were studied in comparison with 316L stainless steel and Mg-Mn-Zn magnesium alloy to reveal the possibility of pure iron as a biodegradable biomaterial. Both electrochemical and weight loss tests showed that pure iron showed a relatively high corrosion rate at the first several days and then decreased to a low level during the following immersion due to the formation of phosphates on the surface. However, the corrosion of pure iron did not cause significant increase in pH value to the solution. In comparison with 316L and Mg-Mn-Zn alloy, the pure iron exhibited biodegradable property in a moderate corrosion rate. Pure iron possessed similar dynamic blood clotting time, prothrombin time and plasma recalcification time to 316L and Mg-Mn-Zn alloy, but a lower hemolysis ratio and a significant lower number density of adhered platelets. MTT results revealed that the extract except the one with 25% 24 h extract actually displayed toxicity to cells and the toxicity increased with the increasing of the iron ion concentration and the incubation time. It was thought there should be an iron ion concentration threshold in the effect of iron ion on the cell toxicity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.