ArticleSarcoma2010
Sclerosing epithelioid fibrosarcoma of the bone: a case report of high resistance to chemotherapy and a survey of the literature.
Article in Sarcoma, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Sclerosing epithelioid fibrosarcoma of the bone: a systematic review of radiologic findings and associated clinical features.Annals of medicine and surgery (2012) · 2026Article
- Rare Case of Sclerosing Epithelioid Fibrosarcoma of the Thoracic Spine.Case reports in orthopedics · 2026Article
- Thoracic Spinal Sclerosing Epithelioid Fibrosarcoma Mimicking Schwannoma: Case Report and Literature Review.Current oncology (Toronto, Ont.) · 2025Review
- A case report from osteosarcoma to SEF: A diagnostic pitfall with a rare metastatic pattern.Radiology case reports · 2025Article
- Sclerosing epithelioid fibrosarcoma of bone with hybrid features: clinicopathologic, radiologic, and molecular analysis of three cases.Skeletal radiology · 2024Article
- Sclerosing epithelioid fibrosarcoma of the foot: A case report.Clinical case reports · 2023Article
- Metastatic pediatric sclerosing epithelioid fibrosarcoma.Cold Spring Harbor molecular case studies · 2021Review
- Low-Grade Fibromyxoid Sarcoma of the Back.Cureus · 2021Article
- Sclerosing epithelioid fibrosarcoma of bone: morphological, immunophenotypical, and molecular findings of 9 cases.Virchows Archiv : an international journal of pathology · 2021Article
- Clinical and molecular characterization of primary sclerosing epithelioid fibrosarcoma of bone and review of the literature.Genes, chromosomes & cancer · 2020Review
- Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula.Frontiers in oncology · 2020Article
- Sclerosing Epithelioid Fibrosarcoma of the Jaw: Late Recurrence from a Low Grade Fibromyxoid Sarcoma.Head and neck pathology · 2018Article
- Clinical Characteristics and efficacy of chemotherapy in sclerosing epithelioid fibrosarcoma.Medical oncology (Northwood, London, England) · 2018Article
- Sclerosing Epithelioid Fibrosarcoma of the Coccyx: A Case Report and Review of Literature.Cureus · 2018Article
- Sclerosing epithelioid fibrosarcoma.Wiener medizinische Wochenschrift (1946) · 2017Article
- Skull sclerosing epithelioid fibrosarcoma: A case report and review of the literature.Oncology letters · 2016Article
- Sclerosing epithelioid fibrosarcoma of the thigh: report of two cases with synchronous bone metastases.Virchows Archiv : an international journal of pathology · 2015Article
- Radiofrequency ablation and percutaneous permanent iodine-125 implantation as salvage therapy for giant recurrent sclerosing epithelioid fibrosarcoma of the chest wall: A case report.Oncology letters · 2015Article
- ¹⁸F-fluorodeoxyglucose PET/CT features and correlations with histopathologic characteristics in sclerosing epithelioid fibrosarcoma.International journal of clinical and experimental pathology · 2014Review
- Sclerosing Epithelioid Fibrosarcoma of the Parietal Bone and Adjacent Meninges in an Adolescent: A Case Report.World journal of oncology · 2013Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sclerosing epithelioid fibrosarcoma (SEF) is a rare soft tissue sarcoma mostly occurring in extraosseous sites. SEF represents a clinically challenging entity especially because no standardized treatment regimens are available. Intraosseous localization is an additional challenge with respect to the therapeutical approach. We report on a 16-year-old patient with SEF of the right proximal tibia. The patient underwent standardized neoadjuvant chemotherapy analogous to the EURAMOS-1 protocol for the treatment of osteosarcoma followed by tumor resection and endoprosthetic reconstruction. Histopathological analysis of the resected tumor showed >90% vital tumor cells suggesting no response to chemotherapy. Therefore, therapy was reassigned to the CWS 2002 High-Risk protocol for the treatment of soft tissue sarcoma. To date (22 months after diagnosis), there is no evidence of relapse or metastasis. Our data suggest that SEF may be resistant to a chemotherapy regimen containing Cisplatin, Doxorubicin, and Methotrexate, which should be considered in planning treatment for patients with SEF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.