Evidence map›Paper›PMID 20395348›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2010

Current perspectives on imaging cardiac stem cell therapy.

Joseph C Wu, M Roselle Abraham, Dara L Kraitchman

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Tracking of stem cells in vivo for cardiovascular applications.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2014
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Development of new technologies for stem cell research.Journal of biomedicine & biotechnology · 2012
    Review
  14. Article
  15. Review
  16. Myocardial substrate and route of administration determine acute cardiac retention and lung bio-distribution of cardiosphere-derived cells.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011
    Article
  17. In vivo imaging for stem cell therapy: new developments and future challenges.European journal of nuclear medicine and molecular imaging · 2011
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Joseph C WuDepartment of Medicine (Cardiology) and Radiology, Stanford University School of Medicine, Stanford, California, USA. joewu@stanford.edu
M Roselle Abraham
Dara L Kraitchman
Johns Hopkins University · USStanford University · US

Funding

X-ray & MR-visible Microencapsulation of Allogeneic Arteriogenic Cell TherapeuticR33HL089029 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KRAITCHMAN, DARA L · 2009 to 2011
$2.1M
Molecular Imaging of Resident Cardiac Stem CellsRC1HL099117 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2009 to 2010
$1000k
Biological Insights into Dynamics of Stem Cell Differentiation and MisbehaviorR21HL091453 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2008 to 2009
$719k
NHLBI NIH HHS R21HL091453-01A1S1NHLBI NIH HHS R33 HL089029NHLBI NIH HHS RC1 HL099117NHLBI NIH HHS RC1HL099117
6 · The paper itself

Abstract

Molecular imaging is a new discipline that makes possible the noninvasive visualization of cellular and molecular processes in living subjects. In the field of cardiovascular regenerative therapy, imaging cell fate after transplantation is a high priority in both basic research and clinical translation. For cell-based therapy to truly succeed, we must be able to track the locations of delivered cells, the duration of cell survival, and any potential adverse effects. The insights gathered from basic research imaging studies will yield valuable insights into better designs for clinical trials. This review highlights the different types of stem cells used for cardiovascular repair, the development of various imaging modalities to track their fate in vivo, and the challenges of clinical translation of cardiac stem cell imaging in the future.

Indexed as

AnimalsCardiovascular DiseasesCell- and Tissue-Based TherapyCell LineageCell SurvivalCell TransplantationCoronary Artery DiseaseDiagnostic ImagingHumansMyocardiumPositron-Emission TomographyStem CellsTime Factors

Identifiers

PMID20395348
PMCPMC3076100
OpenAlexW2067996873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.