Evidence map›Paper›PMID 20395347›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2010

Multimodality imaging of myocardial injury and remodeling.

Christopher M Kramer, Albert J Sinusas, David E Sosnovik, Brent A French, Frank M Bengel

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Molecular Imaging of the Heart.Comprehensive Physiology · 2019
    Review
  6. Article
  7. Review
  8. Novel Imaging Techniques for Heart Failure.Cardiac failure review · 2016
    Article
  9. Article
  10. Review
  11. Review
  12. Cardiac hybrid imaging.European journal of nuclear medicine and molecular imaging · 2014
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Cardiovascular molecular imaging: the road ahead.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Christopher M KramerDepartments of Medicine and Radiology, University of Virginia Health System, 1215 Lee St., Box 800170, Charlottesville, VA 22908, USA. ckramer@virginia.edu
Albert J Sinusas
David E Sosnovik
Brent A French
Frank M Bengel
Harvard University Press · USImaging Center · USJohns Hopkins University · USUniversity of Virginia Health System · USYale University · US

Funding

Non-Invasive Methods for Imaging Myocardial AngiogenesisR01HL065662 · NHLBI · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2001 to 2009
$3.2M
Imaging of MMP activation and myocardial strainsR01HL078650 · NHLBI · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2004 to 2007
$2.3M
Molecular and Microstructural Imaging of Cardiomyocyte Apoptosis and AutophagyR01HL093038 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SOSNOVIK, DAVID E · 2008 to 2012
$2.2M
GENE THERAPY FOR MYOCARDIAL STUNNING AND INFARCTIONR01HL058582 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI FRENCH, BRENT A · 1997 to 2006
$872k
Magnetic Resonance Imaging of Cardiomyocyte ApoptosisK08HL079984 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SOSNOVIK, DAVID E · 2005 to 2009
$661k
NHLBI NIH HHS K08 HL079984NHLBI NIH HHS R01 HL058582NHLBI NIH HHS R01 HL065662NHLBI NIH HHS R01 HL078650NHLBI NIH HHS R01 HL093038
6 · The paper itself

Abstract

Advances in cardiovascular molecular imaging have come at a rapid pace over the last several years. Multiple approaches have been taken to better understand the structural, molecular, and cellular events that underlie the progression from myocardial injury to myocardial infarction (MI) and, ultimately, to congestive heart failure. Multimodality molecular imaging including SPECT, PET, cardiac MRI, and optical approaches is offering new insights into the pathophysiology of MI and left ventricular remodeling in small-animal models. Targets that are being probed include, among others, angiotensin receptors, matrix metalloproteinases, integrins, apoptosis, macrophages, and sympathetic innervation. It is only a matter of time before these advances are applied in the clinical setting to improve post-MI prognostication and identify appropriate therapies in patients to prevent the onset of congestive heart failure.

Indexed as

Ventricular RemodelingAnimalsHeart FailureHumansMacrophagesMagnetic Resonance ImagingMyocardial InfarctionMyocardiumPositron-Emission TomographyReceptor, Angiotensin, Type 1Spectrometry, FluorescenceSympathetic Nervous SystemTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedReceptor, Angiotensin, Type 1

Identifiers

PMID20395347
PMCPMC3078824
OpenAlexW2128276442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.