Evidence map›Paper›PMID 20394044›Full record

ArticleClinical cardiology2010

Prevalence and prognosis of chronic obstructive pulmonary disease among 8167 Middle Eastern patients with acute coronary syndrome.

Hadi A R Hadi, Mohammed Zubaid, Wael Al Mahmeed, Ayman A El-Menyar, Mustafa Ridha, Alawi A Alsheikh-Ali, Rajivir Singh, Nidal Assad, Khalid Al Habib, Jassim Al Suwaidi

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  13. COPD and acute myocardial infarction.European respiratory review : an official journal of the European Respiratory Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Hadi A R HadiDepartment of Cardiology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Mohammed Zubaid
Wael Al Mahmeed
Ayman A El-Menyar
Mustafa Ridha
Alawi A Alsheikh-Ali
Rajivir Singh
Nidal Assad
Khalid Al Habib
Jassim Al Suwaidi
Hamad Medical Corporation · QAShaikh Khalifa Medical City · AEKing Saud University · SAKuwait University · KWQatar Airways (Qatar) · QATufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to report the prevalence and the significance of clinically recognized chronic obstructive pulmonary disease (COPD) during acute coronary syndrome (ACS). HYPOTHESIS: COPD in patients with ACS is associated with worse outcome.

methodsData were derived from a prospective, multicenter, multinational study of 8167 consecutive patients hospitalized with ACS from February to June 2007 in 6 Middle Eastern countries. Data were analyzed according to the presence or absence of COPD. Demographic, management, and in-hospital outcomes were compared.

resultsThe prevalence of COPD was 5.3%. When compared with non-COPD patients, COPD patients were older and more likely to have diabetes, hypertension, and dyslipidemia. Atypical presentations were more common in COPD patients (P = 0.001). COPD patients were less likely to be treated with thrombolytic therapy (P = 0.001), beta-blockers (P = 0.001), and glycoprotein IIb/IIIa inhibitors, and more likely to receive angiotensin-converting enzyme (ACE) inhibitors. Although there was no difference in in-hospital mortality between the 2 groups, patients with COPD were more likely to have heart failure (P = 0.001). Despite the fact that COPD patients with ST-segment elevation myocardial infarction were less likely to receive thrombolytic therapy, they suffered more bleeding complications (2.8% vs 1%, P = 0.04), resulting in prolonged hospitalization. COPD was not an independent predictor of increased in-hospital mortality.

conclusionsIn this large cohort of patients with ACS, the prevalence of COPD was 5.3%. Atypical presentation is common among COPD patients, and this may result in delayed therapy. ACS in COPD patients was associated with higher risk of heart failure and major bleeding complications without increased risk of in-hospital mortality.

Indexed as

Acute Coronary SyndromeAdrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsAspirinChi-Square DistributionComorbidityFemaleHospital MortalityHumansLogistic ModelsMaleMiddle AgedMiddle EastPrevalencePrognosisAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAspirin

Identifiers

PMID20394044
PMCPMC6653010
OpenAlexW2126864270

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.