Evidence map›Paper›PMID 20393477›Full record

ArticleThe Journal of investigative dermatology2010

Common links among the pathways leading to UV-induced immunosuppression.

Gary M Halliday

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

  1. Photocarcinogenesis of the skin: Current status and future trends.The Kaohsiung journal of medical sciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Gary M HallidayDiscipline of Dermatology, Bosch Institute, Sydney Cancer Centre, University of Sydney, Sydney, Australia. garyh@med.usyd.edu.au
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue, Sreevidya et al. demonstrate unexpected similarities in the downstream events of two molecular triggers of UV-induced immunosuppression. Both platelet-activating factor and cis-urocanic acid produced reactive oxygen species (ROS). Blocking both photoproducts reduced UV-induced genetic damage. Vitamin D, another immunosuppressive photoproduct, does not share this property but instead enhances DNA repair. This study therefore links ROS and genetic damage with two molecular triggers of UV immunosuppression.

Indexed as

Ultraviolet RaysDNA DamageHumansImmune ToleranceReactive Oxygen SpeciesReceptors, EstrogenVitamin DReactive Oxygen SpeciesReceptors, EstrogenVitamin D

Identifiers

PMID20393477
OpenAlexW1984350665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.