Evidence map›Paper›PMID 20392923›Full record

ArticleJournal of clinical microbiology2010

Rapid diagnosis of Old World Leishmaniasis by high-resolution melting analysis of the 7SL RNA gene.

Abedelmajeed Nasereddin, Charles L Jaffe

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Assessment of High-Resolution Melting Curve Analysis forPathogens (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Identification ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Species typing in dermal leishmaniasis.Clinical microbiology reviews · 2015
    Review
  13. Review
  14. Comparison of immune regulatory factors in acute and chronic lesions of cutaneous leishmaniasis due to Leishmania major.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Regulatory T-cell profile in early and late lesions of cutaneous leishmaniasis due to Leishmania major.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abedelmajeed NasereddinDepartment of Microbiology and Molecular Genetics, IMIRC, the Kuvin Center for the Study of Infectious and Tropical Diseases, the Hebrew University-Hadassah Medical School, P.O. Box 12272, Jerusalem 91120, Israel.
Charles L Jaffe

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-resolution melt analysis PCR (HRM PCR) for diagnosis of Old World Leishmania was developed using the 7SL RNA gene. Cutaneous leishmaniasis samples were analyzed. Sensitivity and specificity of HRM PCR were significantly better (P < 0.001) than those of internal transcribed spacer 1 PCR and similar to those of kinetoplast DNA PCR.

Indexed as

Transition TemperatureDNA PrimersHumansLeishmaniaLeishmaniasis, CutaneousParasitologyPolymerase Chain ReactionRNA, ProtozoanRNA, Small CytoplasmicSensitivity and SpecificitySignal Recognition Particle7SL RNADNA PrimersRNA, ProtozoanRNA, Small CytoplasmicSignal Recognition Particle

Identifiers

PMID20392923
PMCPMC2884505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.