Evidence map›Paper›PMID 20392919›Full record

ArticleJournal of clinical microbiology2010

Multisite study of cryptosporidiosis in children with diarrhea in India.

Sitara Swarna Rao Ajjampur, Farzana Begum Liakath, Arun Kannan, Priya Rajendran, Rajiv Sarkar, Prabhakar Devarajan Moses, Anna Simon, Indira Agarwal, Ann Mathew, Roberta O'Connor and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Environmental Factors Associated withPathogens (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. High Diversity ofPathogens (Basel, Switzerland) · 2021
    Article
  11. Article
  12. Risk Factors and Spatial Clusters ofInternational journal of environmental research and public health · 2018
    Article
  13. Article
  14. Article
  15. Observational
  16. Natural History of Cryptosporidiosis in a Birth Cohort in Southern India.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  17. Gastroenterology and hepatology from bed to bench · 2017
    Article
  18. Multilocus sequence typing ofThe Indian journal of medical research · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Sitara Swarna Rao AjjampurDepartment of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, India.
Farzana Begum Liakath
Arun Kannan
Priya Rajendran
Rajiv Sarkar
Prabhakar Devarajan Moses
Anna Simon
Indira Agarwal
Ann Mathew
Roberta O'Connor
Honorine Ward
Gagandeep Kang
Christian Medical College & Hospital · INTufts Medical Center · USSt. Stephen’s Hospital · IN

Funding

Multi-disciplinary research training in enteric infectionsD43TW007392 · FIC · CHRISTIAN MEDICAL COLLEGE · PI KANG, GAGANDEEP · 2005 to 2020
$2.9M
Transmission dynamics of cryptosporidial infections in IndiaR01AI075452 · NIAID · CHRISTIAN MEDICAL COLLEGE · PI KANG, GAGANDEEP · 2008 to 2011
$330k
FIC NIH HHS D43 TW007392FIC NIH HHS R03TW2711NIAID NIH HHS AI075452NIAID NIH HHS R01 AI075452
6 · The paper itself

Abstract

Cryptosporidium spp., a common cause of diarrhea in children, were investigated in the first multisite study in India. Diarrheal stools from hospitalized children aged <5 years from Delhi, Trichy, and Vellore were analyzed by microscopy, PCR-restriction fragment length polymorphism (RFLP), and/or sequencing at the small-subunit (SSU) rRNA and Cpgp40/15 loci for species determination and subgenotyping, respectively. Seventy of 2,579 (2.7%) children, 75% of whom were <2 years old, had cryptosporidial diarrhea as determined by microscopy. Genotyping and subgenotyping showed that Cryptosporidium hominis was the most commonly identified species (59/67 children), and subgenotypes Ie, Ia, Ib, and Id were common in all centers. A novel C. parvum subgenotype, IIn, was identified in Vellore. Meteorological analysis revealed a higher rate of cryptosporidial positivity during hotter and drier weather in Delhi.

Indexed as

Child, PreschoolClimateCluster AnalysisCryptosporidiosisCryptosporidiumDiarrheaDNA FingerprintingDNA, ProtozoanDNA, RibosomalFecesFemaleGenes, rRNAGenotypeHumansIndiaInfantDNA, ProtozoanDNA, RibosomalProtozoan ProteinsRNA, ProtozoanRNA, Ribosomal, 18S

Identifiers

PMID20392919
PMCPMC2884513
OpenAlexW2103855849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.