ArticleJournal of clinical microbiology2010
Rapid antifungal susceptibility determination for yeast isolates by use of Etest performed directly on blood samples from patients with fungemia.
Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 56 citations in OpenAlex.
- A five-year survey of dematiaceous fungi in a tropical hospital reveals potential opportunistic species.PloS one · 2014Trial
- Prospective surveillance of Candida auris and assessment of diagnostic approaches in a Belgian hospital.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Emerging antifungal resistance in Candida parapsilosis: the end of the innocence.npj antimicrobials and resistance · 2025Review
- Oleaginous yeasts from Brazilian Cerrado for sustainable biodiesel production using crude glycerol.Antonie van Leeuwenhoek · 2025Article
- Direct Identification of Yeasts from Blood Cultures and Body Fluids Using MALDI-TOF MS with Concurrent Antifungal Susceptibility Testing.Mycopathologia · 2025Article
- In Vitro Assessment of Antifungal and Antibiofilm Efficacy of Commercial Mouthwashes againstAntibiotics (Basel, Switzerland) · 2024Article
- Selection of Autochthonous Yeasts Isolated from the Intestinal Tracts of Cobia Fish (Journal of fungi (Basel, Switzerland) · 2023Article
- Evaluation of the polyphenolic profile of native Ecuadorian stingless bee honeys (Current research in food science · 2023Article
- Chemical Composition, Antioxidant, Anti-Diabetic, Anti-Acetylcholinesterase, Anti-Inflammatory, and Antimicrobial Properties ofLife (Basel, Switzerland) · 2022Article
- Antifungal Activity of Natural Compounds vs.Antibiotics (Basel, Switzerland) · 2022Article
- Direct Fluconazole Disk Susceptibility Testing for Candida glabrata-Positive Blood Cultures.Journal of clinical microbiology · 2021Article
- Evaluation of the effect of the gold nanoparticles prepared by green chemistry on the treatment of cutaneous candidiasis.Current medical mycology · 2021Article
- Can We Improve Antifungal Susceptibility Testing?Frontiers in cellular and infection microbiology · 2021Review
- Azole and Amphotericin B MIC Values againstAntimicrobial agents and chemotherapy · 2020Article
- Epidemiological Trends of Fungemia in Greece with a Focus on Candidemia during the Recent Financial Crisis: a 10-Year Survey in a Tertiary Care Academic Hospital and Review of Literature.Antimicrobial agents and chemotherapy · 2020Review
- Antifungal Susceptibly Testing by Concentration Gradient Strip Etest Method for Fungal Isolates: A Review.Journal of fungi (Basel, Switzerland) · 2019Review
- Detection of Echinocandin-ResistantAntimicrobial agents and chemotherapy · 2019Article
- Resistance to Echinocandins in Candida Can Be Detected by Performing the Etest Directly on Blood Culture Samples.Antimicrobial agents and chemotherapy · 2018Article
- Evaluation of direct antifungal susceptibility testing methods of Candida spp. from positive blood culture bottles.Journal of clinical laboratory analysis · 2018Article
- The Etest Performed Directly on Blood Culture Bottles Is a Reliable Tool for Detection of Fluconazole-Resistant Candida albicans Isolates.Antimicrobial agents and chemotherapy · 2017Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We prospectively determined the antifungal susceptibility of yeast isolates causing fungemia using the Etest on direct blood samples (195 prospectively collected and 133 laboratory prepared). We compared the Etest direct (24 h of incubation) with CLSI M27-A3 and the standard Etest methodologies for fluconazole, voriconazole, posaconazole, isavuconazole, caspofungin, and amphotericin B. Strains were classified as susceptible, resistant, or nonsusceptible using CLSI breakpoints (voriconazole breakpoints were used for posaconazole and isavuconazole). Categorical errors between Etest direct and CLSI M27-A3 for azoles were mostly minor. No errors were detected for caspofungin, and high percentages of major errors were detected for amphotericin B. For the azoles, false susceptibility (very major errors) was found in only two (0.6%) isolates (Candida tropicalis and C. glabrata). False resistance (major errors) was detected in 46 (14%) isolates for the three azoles (in 23 [7%] after excluding posaconazole). Etest direct of posaconazole yielded a higher number of major errors than the remaining azoles, especially for C. glabrata, Candida spp., and other yeasts. Excluding C. glabrata, Candida spp., and other yeasts, the remaining species did not yield major errors. Etest direct for fluconazole, voriconazole, isavuconazole, and caspofungin shows potential as an alternative to the CLSI M27-A3 procedure for performing rapid antifungal susceptibility tests on yeast isolates from patients with fungemia. Etest direct is a useful tool to screen for the presence of azole-resistant and caspofungin-nonsusceptible strains.
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