Evidence map›Paper›PMID 20392477›Full record

ReviewThe Journal of allergy and clinical immunology2010

Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract.

Dagmar Simon, Andrew Wardlaw, Marc E Rothenberg

Abstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Review
  3. The Dynamic Evolution of Eosinophilic Esophagitis.Diagnostics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Eosinophils and melanoma: Implications for immunotherapy.Pigment cell & melanoma research · 2022
    Review
  7. Article
  8. Article
  9. Wells Syndrome - An Odyssey.Open access Macedonian journal of medical sciences · 2019
    Article
  10. Article
  11. Serum eosinophilic cationic protein is correlated with food impaction and endoscopic severity in eosinophilic esophagitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Article
  12. Article
  13. A Management Algorithm for Mitomycin C Induced Cystitis.Bladder cancer (Amsterdam, Netherlands) · 2017
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Eosinophilia in Hematologic Disorders.Immunology and allergy clinics of North America · 2015
    Review
  19. Spectrum of Eosinophilic End-Organ Manifestations.Immunology and allergy clinics of North America · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dagmar SimonDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Andrew Wardlaw
Marc E Rothenberg

Funding

TSLP, IL-9-producing mucosal mast cells, and allergic inflammationU19AI070235 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI LISA J MARTIN · 2006 to 2026
$31.3M
VITAMIN K DEFICIENCY IN CHOLESTATIC LIVER DISEASEM01RR008084 · NCRR · CINCINNATI CHILDRENS HOSP MED CTR · PI STRAUSS, ARNOLD W · 1994 to 2009
$20.6M
Unique Effects of IL-13 in Asthma: Mechanistic AnalysisP01HL076383 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2004 to 2008
$10.1M
REGULATION OF GASTROINTESTINAL EOSINOPHILSR01AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 1999 to 2024
$4.5M
Regulation of Gastrointestinal EosinophilsR37AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2010 to 2019
$3.6M
IL-13 and Eosinophilic EsophagitisR01DK076893 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2007 to 2011
$3.1M
IL-13 Associated Eosinophil Lung ResponsesR01AI083450 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2009 to 2013
$1.9M
Role of arginase in allergic airway inflammationR01AI053479 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2003 to 2007
$1.8M
A multi-center clinical trial of 1760 mcg of daily swallowed fluticasone vs. placU01AI088806 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2009 to 2010
$1.1M
Eosinophil, Chemokine and IL-13 Cooperativity in AsthmaR01AI057803 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2004 to 2007
$731k
MECHANISMS OF EOSINOPHILIA IN EXPERIMENTAL ASTHMAR01AI042242 · NIAID · CHILDREN'S HOSPITAL MED CTR (CINCINNATI) · PI ROTHENBERG, MARC E. · 1998 to 2002
$729k
NCRR NIH HHS M01 RR008084NHLBI NIH HHS P01 HL076383NIAID NIH HHS R01 AI042242NIAID NIH HHS R01 AI045898NIAID NIH HHS R01 AI053479NIAID NIH HHS R01 AI057803NIAID NIH HHS R01 AI083450NIAID NIH HHS R37 AI045898NIAID NIH HHS U01 AI088806NIAID NIH HHS U19 AI070235NIDDK NIH HHS R01 DK076893
6 · The paper itself

Abstract

Eosinophils are multifunctional leukocytes that increase in various tissues in patients with a variety of disorders. Locally, they can be involved in the initiation and propagation of diverse inflammatory responses. In this review the clinical association of eosinophils with diseases of the skin, lung, and gastrointestinal tract is summarized. An approach to determining the causal role of eosinophils in these diseases is presented. Recent findings concerning molecular diagnosis, cause, and treatment are discussed.

Indexed as

AsthmaCellulitisDermatitis, AtopicEosinophiliaEosinophilsEsophagitisGastrointestinal DiseasesHumansHypereosinophilic SyndromeOrgan SpecificityPulmonary EosinophiliaSkin Diseases

Identifiers

PMID20392477
PMCPMC2902687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.