Evidence map›Paper›PMID 20392138›Full record

ReviewZebrafish2010

Oligonucleotide-based tools for studying zebrafish development.

Ilya A Shestopalov, James K Chen

Abstract readReview
In one paragraph

Review in Zebrafish, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Bicyclic Caged Morpholino Oligonucleotides for Optical Gene Silencing.Chembiochem : a European journal of chemical biology · 2022
    Article
  4. Review
  5. Optical Control of MicroRNA Function in Zebrafish Embryos.Journal of the American Chemical Society · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. New insights into signaling during myelination in zebrafish.Current topics in developmental biology · 2011
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ilya A ShestopalovDepartment of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
James K Chen

Funding

Chemical Embryology: Technologies for Manipulating and Visualizing DevelopmentDP1OD003792 · OD · STANFORD UNIVERSITY · PI CHEN, JAMES K · 2008 to 2011
$3.2M
Photochemical Regulation of Embryonic Gene ExpressionR01GM072600 · NIGMS · STANFORD UNIVERSITY · PI CHEN, JAMES K · 2005 to 2009
$1.6M
NIGMS NIH HHS R01 GM072600NIH HHS DP1 OD003792
6 · The paper itself

Abstract

Synthetic and nonnatural oligonucleotides have been used extensively to interrogate gene function in zebrafish. In this review, we survey the capabilities and limitations of various oligonucleotide-based technologies for perturbing RNA function and tracking RNA expression. We also examine recent strategies for achieving spatiotemporal control of oligonucleotide function, particularly light-gated technologies that exploit the optical transparency of zebrafish embryos.

Indexed as

Genetic TechniquesAnimalsGene Expression Regulation, DevelopmentalOligonucleotidesRNAZebrafishOligonucleotidesRNA

Identifiers

PMID20392138
PMCPMC2860060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.