ArticleProteomics2010
Analysis of hepatic glycogen-associated proteins.
Article in Proteomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 95 citations in OpenAlex.
- Glycogen-dependent demixing of frog egg cytoplasm at increased crowding.Biophysical journal · 2026Article
- Targeted glycophagy ATG8 therapy reverses diabetic heart disease in mice and in human engineered cardiac tissues.Nature cardiovascular research · 2025Article
- Targeted glycophagy ATG8 therapy reverses diabetic heart disease in mice and in human engineered cardiac tissues.bioRxiv : the preprint server for biology · 2025Article
- Does AMPK bind glycogen in skeletal muscle or is the relationship correlative?Essays in biochemistry · 2024Review
- Pathomorphogenesis of Glycogen-Ground Glass Hepatocytic Inclusions (Polyglucosan Bodies) in Children after Liver Transplantation.International journal of molecular sciences · 2022Article
- Dynamics of the Glycogen β-Particle Number in Rat Hepatocytes during Glucose Refeeding.International journal of molecular sciences · 2022Article
- Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.Cell metabolism · 2021Article
- Review
- From Prokaryotes to Eukaryotes: Insights Into the Molecular Structure of Glycogen Particles.Frontiers in molecular biosciences · 2021Review
- Starch and Glycogen Analyses: Methods and Techniques.Biomolecules · 2020Review
- Recent progress in the structure of glycogen serving as a durable energy reserve in bacteria.World journal of microbiology & biotechnology · 2020Review
- Methodological considerations for studies of brain glycogen.Journal of neuroscience research · 2019Review
- Brain Glycogen Structure and Its Associated Proteins: Past, Present and Future.Advances in neurobiology · 2019Review
- Interactive Roles for AMPK and Glycogen from Cellular Energy Sensing to Exercise Metabolism.International journal of molecular sciences · 2018Review
- The ER - Glycogen Particle - Phagophore Triangle: A Hub Connecting Glycogenolysis and Glycophagy?Pathology oncology research : POR · 2018Review
- Article
- The unique evolution of the carbohydrate-binding module CBM20 in laforin.FEBS letters · 2018Article
- On the Role of Catabolic Enzymes in Biosynthetic Models of Glycogen Molecular Weight Distributions.ACS omega · 2017Article
- Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice.The Journal of biological chemistry · 2017Article
- Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations.Nature communications · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Glycogen particles are associated with a population of proteins that mediate its biological functions, including: management of glucose flux into and out of the glycogen particle, maintenance of glycogen structure and regulation of particle size, number, and cellular location. A survey of the glycogen-associated proteome would be predicted to identify the relative representation of known members of this population, and associations with unexpected proteins that have the potential to mediate other functions of the glycogen particle. We therefore purified glycogen particles from both mouse and rat liver, using different techniques, and analyzed the resulting tryptic peptides by MS. We also specifically eluted glycogen-binding proteins from the pellet using malto-oligosaccharides. Comparison of the rat and mouse populations, and analysis of specifically eluted proteins allow some conclusions to be made about the hepatic glycogen sub-proteome. With the exception of glycogen branching enzyme all glycogen metabolic proteins were detected. Novel associations were identified, including ferritin and starch-binding domain protein 1, a protein that contains both a transmembrane endoplasmic reticulum signal peptide and a carbohydrate-binding module. This study therefore provides insight into the organization of the glycogen proteome, identifies other associated proteins and provides a starting point to explore the dynamic nature and cellular distribution of this metabolically important protein population.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.