ArticleIndian journal of pharmaceutical sciences2008
Isolation of liver aldehyde oxidase containing fractions from different animals and determination of kinetic parameters for benzaldehyde.
Article in Indian journal of pharmaceutical sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- In Vitro Metabolism by Aldehyde Oxidase Leads to Poor Pharmacokinetic Profile in Rats for c-Met Inhibitor MET401.European journal of drug metabolism and pharmacokinetics · 2019Article
- Role of bitter leaf (International journal of veterinary science and medicine · 2018Article
- Kinetic characterization of a novel endo-β-N-acetylglucosaminidase on concentrated bovine colostrum whey to release bioactive glycans.Enzyme and microbial technology · 2015Article
- Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats.American journal of physiology. Heart and circulatory physiology · 2008Article
- Evaluation of vanillin as a probe drug for aldehyde oxidase and phenotyping for its activity in a Western Indian Cohort.Indian journal of pharmacologyArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
Aldehyde oxidase activity containing fractions from rabbit, guinea pig, rat and mouse livers were obtained by heat treatment and ammonium sulfate precipitation. Aldehyde oxidase activity was observed in rabbit and guinea pig livers, while aldehyde oxidase activity was absent in rat and mouse liver fractions. Enzyme kinetic parameters, K(m) and V(max), were determined for the oxidation of benzaldehyde to benzoic acid by rabbit and guinea pig liver fractions, by spectrophotometric method, with potassium ferricyanide as the electron acceptor. The K(m) values obtained for both animal liver fractions were in the range of 10.3-19.1 muM.
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