ArticleJournal of analytical atomic spectrometry2010
Metal-Containing Polystyrene Beads as Standards for Mass Cytometry.
Article in Journal of analytical atomic spectrometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- High-throughput multiplexed serology via the mass-spectrometric analysis of isotopically barcoded beads.Nature biomedical engineering · 2025Article
- Determination of carbon in microplastics and single cells by total consumption microdroplet ICP-TOFMS.Analytical and bioanalytical chemistry · 2024Article
- Online microdroplet calibration for accurate nanoparticle quantification in organic matrices.Analytical and bioanalytical chemistry · 2022Article
- Living in a transient world: ICP-MS reinventedChemical science · 2022Review
- Exploring Sensitive Label-Free Multiplex Analysis with Raman-Coded Microbeads and SERS-Coded Reporters.Biosensors · 2022Article
- Establishing CD19 B-cell reference control materials for comparable and quantitative cytometric expression analysis.PloS one · 2021Article
- High Throughput Multi-Omics Approaches for Clinical Trial Evaluation and Drug Discovery.Frontiers in immunology · 2021Review
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).European journal of immunology · 2019Article
- Guidelines for the use of flow cytometry and cell sorting in immunological studies.European journal of immunology · 2017Article
- Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data.Methods (San Diego, Calif.) · 2015Article
- Single-cell mass cytometry for analysis of immune system functional states.Current opinion in immunology · 2013Review
- Normalization of mass cytometry data with bead standards.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2013Article
- A deep profiler's guide to cytometry.Trends in immunology · 2012Review
- Surface Functionalization Methods to Enhance Bioconjugation in Metal-Labeled Polystyrene Particles.Macromolecules · 2011Article
- Bio-Functional, Lanthanide-Labeled Polymer Particles by Seeded Emulsion Polymerization and their Characterization by Novel ICP-MS Detection.Journal of analytical atomic spectrometry · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
We examine the suitability of metal-containing polystyrene beads for the calibration of a mass cytometer instrument, a single particle analyser based on an inductively coupled plasma ion source and a time of flight mass spectrometer. These metal-containing beads are also verified for their use as internal standards for this instrument. These beads were synthesized by multiple-stage dispersion polymerization with acrylic acid as a comonomer. Acrylic acid acts as a ligand to anchor the metal ions within the interior of the beads. Mass cytometry enabled the bead-by-bead measurement of the metal-content and determination of the metal-content distribution. Beads synthesized by dispersion polymerization that involved three stages were shown to have narrower bead-to-bead variation in their lanthanide content than beads synthesized by 2-stage dispersion polymerization. The beads exhibited insignificant release of their lanthanide content to aqueous solutions of different pHs over a period of six months. When mixed with KG1a or U937 cell lines, metal-containing polymer beads were shown not to affect the mass cytometry response to the metal content of element-tagged antibodies specifically attached to these cells.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.