Evidence map›Paper›PMID 20387895›Full record

ArticleJournal of the American Chemical Society2010

Total synthesis of (+)-complanadine A using an iridium-catalyzed pyridine C-H functionalization.

Daniel F Fischer, Richmond Sarpong

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Skeletal Editing Strategies Driven by Total Synthesis.Accounts of chemical research · 2025
    Article
  3. Advancing Total Synthesis Through Skeletal Editing.Accounts of chemical research · 2025
    Article
  4. Article
  5. Comparative analysis of complanadine A total syntheses.Beilstein journal of organic chemistry · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Metal-Free Intermolecular C-H Borylation of N-Heterocycles at B-B Multiple Bonds.Angewandte Chemie (International ed. in English) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel F FischerDepartment of Chemistry, University of California, Berkeley, California 94720, USA.
Richmond Sarpong

Funding

Total Synthesis of Bioactive Natural ProductsR01GM086374 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SARPONG, RICHMOND · 2009 to 2018
$2.7M
NIGMS NIH HHS R01 GM086374NIGMS NIH HHS R01 GM086374-01
6 · The paper itself

Abstract

The total synthesis of the Lycopodium alkaloid complanadine A, which is an unsymmetrical dimer of lycodine, was achieved by exploiting a common tetracyclic precursor. Key to the success of the synthesis was the development of a late-stage site-selective C-H functionalization of a pyridine moiety to arrive at a key boronic ester intermediate.

Indexed as

CarbonCatalysisHeterocyclic Compounds, 4 or More RingsHydrogenIridiumLycopodiumPyridinesCarboncomplanadine AHeterocyclic Compounds, 4 or More RingsHydrogenIridiumpyridinePyridines

Identifiers

PMID20387895
PMCPMC2867450

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.