Evidence map›Paper›PMID 20387026›Full record

ReviewCerebellum (London, England)2010

Novel approaches to studying the genetic basis of cerebellar development.

Samin A Sajan, Kathryn E Waimey, Kathleen J Millen

Abstract readReview
In one paragraph

Review in Cerebellum (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Cellular commitment in the developing cerebellum.Frontiers in cellular neuroscience · 2014
    Review
  4. Article
  5. Article
  6. Tissue plasminogen activator regulates Purkinje neuron development and survival.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  7. Intracerebellar application of P19-derived neuroprogenitor and naive stem cells to Lurcher mutant and wild type B6CBA mice.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samin A SajanDepartment of Human Genetics, The University of Chicago, 920 E 58th Street, CLSC 319, Chicago, IL 60637, USA.
Kathryn E Waimey
Kathleen J Millen
University of Chicago · US

Funding

Roles of Zic Genes in Vertebrate Hindbrain DevelopmentR01NS050386 · NINDS · UNIVERSITY OF CHICAGO · PI MILLEN, KATHLEEN JOYCE · 2004 to 2010
$2.1M
NINDS NIH HHS R01 NS050386
6 · The paper itself

Abstract

The list of genes that when mutated cause disruptions in cerebellar development is rapidly increasing. The study of both spontaneous and engineered mouse mutants has been essential to this progress, as it has revealed much of our current understanding of the developmental processes required to construct the mature cerebellum. Improvements in brain imaging, such as magnetic resonance imaging (MRI) and the emergence of better classification schemes for human cerebellar malformations, have recently led to the identification of a number of genes which cause human cerebellar disorders. In this review we argue that synergistic approaches combining classical molecular techniques, genomics, and mouse models of human malformations will be essential to fuel additional discoveries of cerebellar developmental genes and mechanisms.

Indexed as

AnimalsCerebellumGenetic TechniquesHumansMiceMice, Mutant Strains

Identifiers

PMID20387026
PMCPMC2921561
OpenAlexW2018172009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.