Evidence map›Paper›PMID 20386998›Full record

ArticleJournal of general internal medicine2010

Understanding racial disparities in treatment intensification for hypertension management.

Meredith Manze, Adam J Rose, Michelle B Orner, Dan R Berlowitz, Nancy R Kressin

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Meredith ManzeSection of General Internal Medicine, Boston University School of Medicine, Boston, MA, USA. meredith.manze@bmc.org
Adam J Rose
Michelle B Orner
Dan R Berlowitz
Nancy R Kressin
Bedford VA Research Corporation · USBoston University · USVA Boston Healthcare System · US

Funding

Hypertension Control &Therapy AdherenceR01HL072814 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KRESSIN, NANCY R. · 2004 to 2007
$2.6M
NHLBI NIH HHS R01 HL072814
6 · The paper itself

Abstract

backgroundDisparities in blood pressure (BP) control may be a function of disparities in treatment intensification (TI).

objectiveTo examine racial differences in TI, understand modifiable factors that may mediate this relationship, and explore the relative effects of TI and race on blood pressure.

designProspective cohort study.

participantsParticipants were 819 black and white patients with hypertension from an urban, safety-net hospital MAIN MEASURES: We sequentially explored the effects of patient race, sociodemographic and clinical characteristics, beliefs about BP/medications, perceptions of provider/discrimination, sodium intake, medication adherence, and provider counseling on TI, performing a series of random effects analyses. To assess the effects of race and TI on BP, we performed linear regressions, using systolic BP (SBP) as the outcome. KEY

resultsUnadjusted analyses and those including sociodemographic and clinical characteristics revealed that black patients had less TI than whites (-0.31 vs.-0.24, p < 0.001), but adjustment for patient beliefs and experiences eliminated the effects of race (beta =-0.02, p = 0.5). Increased patient concerns about BP medications were related to lower TI, as was more provider counseling (beta =-0.06, p = 0.02 and beta = -0.01, p = 0.001, respectively). In the unadjusted analysis, black race was a significant predictor of SBP (134 mm/Hg for blacks vs. 131 mm/Hg for whites, p = 0.009), but when both race and TI were included in the model, TI was a significant predictor of SBP (final SBP 2.0 mm/Hg lower for each additional therapy increase per 10 visits, p < 0.001), while race was not (Blacks 1.6 mm/Hg higher than whites, p = 0.17).

conclusionsImproved patient-provider communication targeted towards addressing patient concerns about medications may have the potential to reduce racial disparities in TI and ultimately, BP control.

Indexed as

Healthcare DisparitiesAntihypertensive AgentsBlack or African AmericanBlood PressureFemaleHealth Knowledge, Attitudes, PracticeHumansHypertensionLinear ModelsMaleMedication AdherenceMiddle AgedMultivariate AnalysisProspective StudiesStatistics as TopicSurveys and QuestionnairesAntihypertensive Agents

Identifiers

PMID20386998
PMCPMC2896595
OpenAlexW2009730717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.