ArticleAntimicrobial agents and chemotherapy2010
OXA-24 carbapenemase gene flanked by XerC/XerD-like recombination sites in different plasmids from different Acinetobacter species isolated during a nosocomial outbreak.
Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68 citing papers in PubMed, 106 citations in OpenAlex.
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- CRISPR-Based Gene Editing inPharmaceuticals (Basel, Switzerland) · 2023Review
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- Complete genetic characterization of carbapenem-resistantFrontiers in cellular and infection microbiology · 2023Article
- Mobile genetic elements in Acinetobacter antibiotic-resistance acquisition and dissemination.Annals of the New York Academy of Sciences · 2022Review
- Plasmids as Key Players inInternational journal of molecular sciences · 2022Review
- Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter junii Conferred by Acquisition ofMicrobiology spectrum · 2022Article
- Molecular epidemiology and carbapenem resistance characteristics ofFrontiers in microbiology · 2022Article
- Phylogenomics of two ST1 antibiotic-susceptible non-clinicalMicrobial genomics · 2021Article
- Co-infection of ST2BMC infectious diseases · 2021Article
- A Novel Transferable Resistance-Nodulation-Division Pump Gene Cluster,Antimicrobial agents and chemotherapy · 2021Article
- Analysis of Complete Genome Sequence ofMicroorganisms · 2020Article
- Functional Analysis of theAntibiotics (Basel, Switzerland) · 2020Article
- What do we know about plasmids carried by members of the Acinetobacter genus?World journal of microbiology & biotechnology · 2020Review
- Carbapenemases: TransformingBiomolecules · 2020Review
- Article
8 more citing papers are in PubMed but not listed here.
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7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
A clinical strain of Acinetobacter calcoaceticus resistant to carbapenems was isolated from a blood culture sample from an inpatient in a hospital in Madrid (Spain) during a large outbreak of infection (affecting more than 300 inpatients), caused by a multidrug-resistant Acinetobacter baumannii clone. The carbapenem resistance in both the A. calcoaceticus and A. baumannii clones was due to a bla(OXA-24) gene harbored in different plasmids. The plasmids were fully sequenced, revealing the presence of site-specific recombination binding sites putatively involved in mobilization of the bla(OXA-24) gene. Comparison of plasmids contained in the two strains revealed possible horizontal transmission of resistance genes between the Acinetobacter species.
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