ArticleProceedings of the National Academy of Sciences of the United States of America2010
Correlated physiological and perceptual effects of noise in a tactile stimulus.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Potential role of noise to improve intracortical microstimulation in tactile neuroprostheses.Neural regeneration research · 2021Article
- Response dynamics of rat barrel cortex neurons to repeated sensory stimulation.Scientific reports · 2017Article
- Reward functions of the basal ganglia.Journal of neural transmission (Vienna, Austria : 1996) · 2016Review
- Components and characteristics of the dopamine reward utility signal.The Journal of comparative neurology · 2016Review
- Neural timing signal for precise tactile timing judgments.Journal of neurophysiology · 2016Article
- Dopamine reward prediction-error signalling: a two-component response.Nature reviews. Neuroscience · 2016Review
- Neuronal Reward and Decision Signals: From Theories to Data.Physiological reviews · 2015Review
- Support for the slip hypothesis from whisker-related tactile perception of rats in a noisy environment.Frontiers in integrative neuroscience · 2015Article
- Tactile frequency discrimination is enhanced by circumventing neocortical adaptation.Nature neuroscience · 2014Article
- Tactile perception and working memory in rats and humans.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Diverse thalamocortical short-term plasticity elicited by ongoing stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Behavioral detection of passive whisker stimuli requires somatosensory cortex.Cerebral cortex (New York, N.Y. : 1991) · 2013Article
- Learning not to feel: reshaping the resolution of tactile perception.Frontiers in systems neuroscience · 2013Article
- Behavioral study of whisker-mediated vibration sensation in rats.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
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4 authors.
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Abstract
We investigated connections between the physiology of rat barrel cortex neurons and the sensation of vibration in humans. One set of experiments measured neuronal responses in anesthetized rats to trains of whisker deflections, each train characterized either by constant amplitude across all deflections or by variable amplitude ("amplitude noise"). Firing rate and firing synchrony were, on average, boosted by the presence of noise. However, neurons were not uniform in their responses to noise. Barrel cortex neurons have been categorized as regular-spiking units (putative excitatory neurons) and fast-spiking units (putative inhibitory neurons). Among regular-spiking units, amplitude noise caused a higher firing rate and increased cross-neuron synchrony. Among fast-spiking units, noise had the opposite effect: It led to a lower firing rate and decreased cross-neuron synchrony. This finding suggests that amplitude noise affects the interaction between inhibitory and excitatory neurons. From these physiological effects, we expected that noise would lead to an increase in the perceived intensity of a vibration. We tested this notion using psychophysical measurements in humans. As predicted, subjects overestimated the intensity of noisy vibrations. Thus the physiological mechanisms present in barrel cortex also appear to be at work in the human tactile system, where they affect vibration perception.
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