ArticleNucleic acids research2010
Large-scale detection and analysis of RNA editing in grape mtDNA by RNA deep-sequencing.
Article in Nucleic acids research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 143 citations in OpenAlex.
- Short-read RNA-seq yields lower estimates of A-to-I RNA editing levels than long-read cDNA sequencing.Advanced biotechnology · 2026Article
- Assembly and comparative analysis of the first complete mitochondrial genome of Camellia sinensis var. assamica 'Hainan Dayezhong', endemic to Hainan Province, China.BMC plant biology · 2025Article
- Assembly and analysis of the complete mitochondrial genome of Leonurus japonicus (Lamiaceae).Scientific reports · 2025Article
- Massive RNA Editing in Ascetosporean Mitochondria.Microbes and environments · 2025Article
- Repeat-mediated recombination results in Complex DNA structure of the mitochondrial genome of Trachelospermum jasminoides.BMC plant biology · 2024Article
- Assembly and characterization of the complete mitochondrial genome of Ventilago leiocarpa.Plant cell reports · 2024Article
- Unraveling C-to-U RNA editing events from direct RNA sequencing.RNA biology · 2024Article
- Complete Mitochondrial Genome Assembly of an Upland Wild Rice Species,Life (Basel, Switzerland) · 2023Article
- Genetic diversity ofFrontiers in plant science · 2023Article
- The Mitogenome ofBiology · 2022Article
- Evolution of mitochondrial RNA editing in extant gymnosperms.The Plant journal : for cell and molecular biology · 2022Article
- Genome-Wide Identification and Characterization of RNA/DNA Differences Associated with Drought Response in Wheat.International journal of molecular sciences · 2022Article
- Integrative profiling of Epstein-Barr virus transcriptome using a multiplatform approach.Virology journal · 2022Article
- Review
- Detection and Analysis of C-to-U RNA Editing in Rice Mitochondria-Encoded ORFs.Plants (Basel, Switzerland) · 2020Article
- Systematic analyses reveal RNA editing events involved in skeletal muscle development of goat (Capra hircus).Functional & integrative genomics · 2020Article
- Dynamic response of RNA editing to temperature in grape by RNA deep sequencing.Functional & integrative genomics · 2020Article
- Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal.Nature protocols · 2020Article
- miR828 and miR858 regulate VvMYB114 to promote anthocyanin and flavonol accumulation in grapes.Journal of experimental botany · 2019Article
- RNA editing in the forefront of epitranscriptomics and human health.Journal of translational medicine · 2019Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RNA editing is a widespread post-transcriptional molecular phenomenon that can increase proteomic diversity, by modifying the sequence of completely or partially non-functional primary transcripts, through a variety of mechanistically and evolutionarily unrelated pathways. Editing by base substitution has been investigated in both animals and plants. However, conventional strategies based on directed Sanger sequencing are time-consuming and effectively preclude genome wide identification of RNA editing and assessment of partial and tissue-specific editing sites. In contrast, the high-throughput RNA-Seq approach allows the generation of a comprehensive landscape of RNA editing at the genome level. Short reads from Solexa/Illumina GA and ABI SOLiD platforms have been used to investigate the editing pattern in mitochondria of Vitis vinifera providing significant support for 401 C-to-U conversions in coding regions and an additional 44 modifications in non-coding RNAs. Moreover, 76% of all C-to-U conversions in coding genes represent partial RNA editing events and 28% of them were shown to be significantly tissue specific. Solexa/Illumina and SOLiD platforms showed different characteristics with respect to the specific issue of large-scale editing analysis, and the combined approach presented here reduces the false positive rate of discovery of editing events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.