Evidence map›Paper›PMID 20385083›Full record

ArticleMolecular cell2010

King of the castle: competition between repressors and activators on the Mcm1 platform.

Janet Leatherwood, Bruce Futcher

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janet LeatherwoodDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.
Bruce Futcher
Stony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Darieva and coworkers (Darieva et al., 2010) have shown that the repressor Yox1 and the activator Fkh2-Ndd1 associate with opposite sides of the dimeric Mcm1 transcription factor but nevertheless compete for binding; the outcome determines expression of late mitotic genes in yeast.

Indexed as

Gene Expression Regulation, FungalCell Cycle ProteinsForkhead Transcription FactorsHomeodomain ProteinsMinichromosome Maintenance 1 ProteinMultiprotein ComplexesProtein BindingProtein MultimerizationRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCell Cycle ProteinsFkh2 protein, S cerevisiaeForkhead Transcription FactorsHomeodomain ProteinsMinichromosome Maintenance 1 ProteinMultiprotein ComplexesRepressor ProteinsSaccharomyces cerevisiae ProteinsYox1 protein, S cerevisiae

Identifiers

PMID20385083
OpenAlexW2090729608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.