Evidence map›Paper›PMID 20384222›Full record

ReviewAdvances in experimental medicine and biology2010

Inorganic nanoporous membranes for immunoisolated cell-based drug delivery.

Adam Mendelsohn, Tejal Desai

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Advances in islet encapsulation technologies.Nature reviews. Drug discovery · 2017
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam MendelsohnUCSF/UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, University of California, Berkeley, USA.
Tejal Desai

Funding

NANOPOROUS INOGANIC BIOCAPSULESR21EB000570 · NIBIB · BOSTON UNIVERSITY · PI DESAI, TEJAL A. · 2002 to 2003
$193k
NIBIB NIH HHS R21 EB000570
6 · The paper itself

Abstract

Materials advances enabled by nanotecbnology have brought about promising approaches to improve the encapsulation mechanism for immunoisolated cell-based drug delivery. Cell-based drug delivery is a promising treatment for many diseases but has thus far achieved only limited clinical success. Treatment of insulin dependent diabetes mellitus (IDDM) by transplantation of pancreatic beta-cells represents the most anticipated application ofcell-based drug delivery technology. This review outlines the challenges involved with maintaining transplanted cell viability and discusses how inorganic nanoporous membranes may be useful in achieving clinical success.

Indexed as

Drug Delivery SystemsIslets of Langerhans TransplantationMembranes, ArtificialNanostructuresAluminum OxideAnimalsDiabetes Mellitus, Type 1Drug CompoundingHumansImmunosuppressive AgentsInsulinPorositySiliconTitaniumAluminum OxideImmunosuppressive AgentsInsulinMembranes, ArtificialSiliconTitaniumtitanium dioxide

Identifiers

PMID20384222
PMCPMC4046704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.