Evidence map›Paper›PMID 20383782›Full record

ArticleTropical animal health and production2010

Distribution and characterization of the Escherichia coli heat-stable enterotoxin (STa) receptor throughout the intestinal tract of newborn camels (Camelus dromedaries).

Ahmad M Al-Majali, Mohammad S Khalifeh

Abstract read
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Article in Tropical animal health and production, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ahmad M Al-MajaliDepartment of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P. O. Box 3030, Irbid, 22110, Jordan. almajali@just.edu.jo
Mohammad S Khalifeh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat-stable enterotoxin (STa) secretion from Enterotoxigenic Escherichia coli (ETEC) is crucial for the pathogenesis of diarrhea in both animal and human. The goal of this study was to investigate the distribution of the STa-specific receptors in the newborn camel's enterocytes and brush border membrane vesicles (BBMVs). Flow cytometric analysis was used to investigate the density of STa-receptors on enterocytes and BBMVs prepared from anterior jejunum, posterior jejunum, ileum, and colon. Strong density and affinity of STa-receptors was present on enterocytes and BBMVs of the ileum compared to that in the other intestinal segments. It was concluded that the ileum is the major target for STa action in newborn camels.

Indexed as

AnimalsAnimals, NewbornBacterial ToxinsCamelusChromatography, High Pressure LiquidEnterocytesEnterotoxinsEscherichia coli ProteinsFlow CytometryGastrointestinal TractGuanylate CyclaseMicrovilliReceptors, EnterotoxinReceptors, Guanylate Cyclase-CoupledReceptors, PeptideStatistics, NonparametricBacterial ToxinsEnterotoxinsEscherichia coli ProteinsGuanylate Cyclaseheat stable toxin (E coli)Receptors, EnterotoxinReceptors, Guanylate Cyclase-CoupledReceptors, Peptide

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.