Trial reportEuropean journal of nuclear medicine and molecular imaging2010
Simultaneous dual-radionuclide myocardial perfusion imaging with a solid-state dedicated cardiac camera.
Trial report in European journal of nuclear medicine and molecular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- Pooled it
- A randomized, double-blind, crossover comparison of novel continuous bed motion versus traditional bed position whole-body PET/CT imaging.European journal of nuclear medicine and molecular imaging · 2016Trial
- Evaluation of ischaemia in obese patients: feasibility and accuracy of a low-dose protocol with a cadmium-zinc telluride camera.European journal of nuclear medicine and molecular imaging · 2012Trial
- Deep learning prediction of quantitative coronary angiography values using myocardial perfusion images with a CZT camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Feasibility of simultaneousJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Observational
- Simultaneous dual isotopeJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Feasibility of simultaneous dual isotope acquisition for myocardial perfusion imaging with a cadmium zinc telluride camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- EANM procedural guidelines for myocardial perfusion scintigraphy using cardiac-centered gamma cameras.European journal of hybrid imaging · 2019Article
- Comparative Cardiac Phantom Study Using Tc-99m/I-123 and Tl-201/I-123 Tracers with Cadmium-Zinc-Telluride Detector-Based Single-Photon Emission Computed Tomography.Nuclear medicine and molecular imaging · 2019Article
- Low-dose dual-isotope procedure planed for myocardial perfusion CZT-SPECT and assessed through a head-to-head comparison with a conventional single-isotope protocol.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Dual-isotope myocardial perfusion SPECT imaging: Past, present, and future.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, Processing, and Interpretation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Review
- Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical results.EJNMMI physics · 2018Article
- Comparison of conventional and cadmium-zinc-telluride single-photon emission computed tomography for analysis of thallium-201 myocardial perfusion imaging: an exploratory study in normal databases for different ethnicities.The international journal of cardiovascular imaging · 2017Article
- Optimization of a simultaneous dual-isotopeJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Dual isotope and multidetector camera: The best choices for a specific end-point.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- SPECT and PET in ischemic heart failure.Heart failure reviews · 2017Review
- Performance of cardiac cadmium-zinc-telluride gamma camera imaging in coronary artery disease: a review from the cardiovascular committee of the European Association of Nuclear Medicine (EANM).European journal of nuclear medicine and molecular imaging · 2016Review
- Novel SPECT Technologies and Approaches in Cardiac Imaging.Cardiovascular innovations and applications · 2016Article
- Which SPECT for today, which SPECT for tomorrow?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 4 countries.
Funding
Abstract
purposeWe compared simultaneous dual-radionuclide (DR) stress and rest myocardial perfusion imaging (MPI) with a novel solid-state cardiac camera and a conventional SPECT camera with separate stress and rest acquisitions.
methodsOf 27 consecutive patients recruited, 24 (64.5+/-11.8 years of age, 16 men) were injected with 74 MBq of (201)Tl (rest) and 250 MBq (99m)Tc-MIBI (stress). Conventional MPI acquisition times for stress and rest are 21 min and 16 min, respectively. Rest (201)Tl for 6 min and simultaneous DR 15-min list mode gated scans were performed on a D-SPECT cardiac scanner. In 11 patients DR D-SPECT was performed first and in 13 patients conventional stress (99m)Tc-MIBI SPECT imaging was performed followed by DR D-SPECT. The DR D-SPECT data were processed using a spill-over and scatter correction method. DR D-SPECT images were compared with rest (201)Tl D-SPECT and with conventional SPECT images by visual analysis employing the 17-segment model and a five-point scale (0 normal, 4 absent) to calculate the summed stress and rest scores. Image quality was assessed on a four-point scale (1 poor, 4 very good) and gut activity was assessed on a four-point scale (0 none, 3 high).
resultsConventional MPI studies were abnormal at stress in 17 patients and at rest in 9 patients. In the 17 abnormal stress studies DR D-SPECT MPI showed 113 abnormal segments and conventional MPI showed 93 abnormal segments. In the nine abnormal rest studies DR D-SPECT showed 45 abnormal segments and conventional MPI showed 48 abnormal segments. The summed stress and rest scores on conventional SPECT and DR D-SPECT were highly correlated (r=0.9790 and 0.9694, respectively). The summed scores of rest (201)Tl D-SPECT and DR-DSPECT were also highly correlated (r=0.9968, p<0.0001 for all). In six patients stress perfusion defects were significantly larger on stress DR D-SPECT images, and five of these patients were imaged earlier by D-SPECT than by conventional SPECT.
conclusionFast and high-quality simultaneous DR MPI is feasible with D-SPECT in a single imaging session with comparable diagnostic performance and image quality to conventional SPECT and to a separate rest (201)Tl D-SPECT acquisition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.