ArticleMolecular & general genetics : MGG1991
Analysis of conserved domains identifies a unique structural feature of a chloroplast heat shock protein.
Article in Molecular & general genetics : MGG, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Metabolic Reprogramming in Chloroplasts under Heat Stress in Plants.International journal of molecular sciences · 2018Review
- The chloroplast-localized small heat shock protein Hsp21 associates with the thylakoid membranes in heat-stressed plants.Protein science : a publication of the Protein Society · 2017Article
- Structural model of dodecameric heat-shock protein Hsp21: Flexible N-terminal arms interact with client proteins while C-terminal tails maintain the dodecamer and chaperone activity.The Journal of biological chemistry · 2017Article
- Plastid casein kinase 2 knockout reduces abscisic acid (ABA) sensitivity, thermotolerance, and expression of ABA- and heat-stress-responsive nuclear genes.Journal of experimental botany · 2014Article
- Chloroplast small heat shock protein HSP21 interacts with plastid nucleoid protein pTAC5 and is essential for chloroplast development in Arabidopsis under heat stress.The Plant cell · 2013Article
- Analysis of gene sequences indicates that quantity not quality of chloroplast small HSPs improves thermotolerance in C4 and CAM plants.Plant cell reports · 2012Article
- Overexpression of alfalfa mitochondrial HSP23 in prokaryotic and eukaryotic model systems confers enhanced tolerance to salinity and arsenic stress.Biotechnology letters · 2012Article
- Subunit arrangement in the dodecameric chloroplast small heat shock protein Hsp21.Protein science : a publication of the Protein Society · 2011Article
- Chemical cross-linking of the chloroplast localized small heat-shock protein, Hsp21, and the model substrate citrate synthase.Protein science : a publication of the Protein Society · 2007Article
- Divergent evolution of the chloroplast small heat shock protein gene in the genera Rhododendron (Ericaceae) and Machilus (Lauraceae).Annals of botany · 2007Article
- The heat stress transcription factor HsfA2 serves as a regulatory amplifier of a subset of genes in the heat stress response in Arabidopsis.Plant molecular biology · 2006Article
- Dual role for tomato heat shock protein 21: protecting photosystem II from oxidative stress and promoting color changes during fruit maturation.The Plant cell · 2005Article
- A novel small heat shock protein gene, vis1, contributes to pectin depolymerization and juice viscosity in tomato fruit.Plant physiology · 2003Article
- Substitution of conserved methionines by leucines in chloroplast small heat shock protein results in loss of redox-response but retained chaperone-like activity.Protein science : a publication of the Protein Society · 2001Article
- The expanding family of Arabidopsis thaliana small heat stress proteins and a new family of proteins containing alpha-crystallin domains (Acd proteins).Cell stress & chaperones · 2001Article
- Arabidopsis RTM2 gene is necessary for specific restriction of tobacco etch virus and encodes an unusual small heat shock-like protein.The Plant cell · 2000Article
- Chloroplast small heat shock proteins: evidence for atypical evolution of an organelle-localized protein.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Methionine sulfoxidation of the chloroplast small heat shock protein and conformational changes in the oligomer.Protein science : a publication of the Protein Society · 1999Article
- Isolation and characterization of a mutant protoporphyrinogen oxidase gene from Chlamydomonas reinhardtii conferring resistance to porphyric herbicides.Plant molecular biology · 1998Article
- Evolutionary origin of two genes for chloroplast small heat shock protein of tobacco.Plant molecular biology · 1998Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
Abstract
A low molecular weight heat shock protein which localizes to chloroplasts has been identified in several plant species. This protein belongs to a eukaryotic superfamily of small HSPs, all of which contain a conserved carboxyl-terminal domain. To investigate further the structure of this HSP, we isolated and sequenced cDNA clones for the chloroplast LMW HSPs from Petunia hybrida and Arabidopsis thaliana. The cloning of chloroplast HSPs from these two species enabled us to compare the amino acid sequences of this protein from plant species (petunia, Arabidopsis, pea, soybean and maize) that represent evolutionarily divergent taxonomic subclasses. Three conserved regions were identified, which are designated as regions I, II and III. Regions I and II are also shared by cytoplasmic LMW HSPs and therefore are likely to have functional roles common to all eukaryotic LMW HSPs. In contrast, consensus region III is not found in other LMW HSPs. Secondary structure analysis predicts that this region forms an amphipathic alpha-helix with high conservation of methionine residues on the hydrophobic face and 100% conservation of residues on the hydrophilic face. This structure is similar to three helices, termed "methionine bristles", which are found in a methionine-rich domain of a 54 kDa protein component of signal recognition particle (SRP54). The conservation of regions I and II among LMW cytoplasmic and chloroplast HSPs suggests that these HSPs perform related functions in different cellular compartments. However, identification of the methionine bristle domain suggests that chloroplast HSPs also have unique functions or substrates within the special environment of the chloroplast or other plastids.
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