Evidence map›Paper›PMID 20382326›Full record

ReviewLancet (London, England)2010

Early recognition and prevention of chronic kidney disease.

Matthew T James, Brenda R Hemmelgarn, Marcello Tonelli

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Lancet (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03319888 (Effect of CPAP in the Worsening of Renal Function in Early Stages of Chronic Kidney Disease), which is not on this map. Cited by 264 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
264citing papers in PubMed, 16 pooled it
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03319888 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Effect of CPAP in the Worsening of Renal Function in Early Stages of Chronic Kidney Disease (CKD)

TypeinterventionalSponsorSociedad Española de Neumología y Cirugía TorácicaRan2017 to 2020Enrolled700ConditionsChronic Kidney Insufficiency, Sleep ApneaArmsCPAP, conservative treatment
3 · Its place in the literature

Who cites it

264 citing papers in PubMed, 16 syntheses or guidelines pooled it, 601 citations in OpenAlex.

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  16. A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2015
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204 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Matthew T JamesDepartment of Medicine, University of Calgary, Calgary, AB, Canada.
Brenda R Hemmelgarn
Marcello Tonelli
University of Calgary · CAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease is a common disorder and its prevalence is increasing worldwide. Early diagnosis on the basis of presence of proteinuria or reduced estimated glomerular filtration rate could permit early intervention to reduce the risks of cardiovascular events, kidney failure, and death that are associated with chronic kidney disease. In developed countries, screening for the disorder is most efficient when targeted at high-risk groups including elderly people and those with concomitant illness (such as diabetes, hypertension, or cardiovascular disease) or a family history of chronic kidney disease, although the role of screening in developing countries is not yet clear. Effective strategies are available to slow the progression of chronic kidney disease and reduce cardiovascular risk. Treatment of high blood pressure is recommended for all individuals with, or at risk of, chronic kidney disease. Use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers is preferred for patients with diabetic chronic kidney disease or those with the proteinuric non-diabetic disorder. Glycaemic control can help prevent the onset of early stages of chronic kidney disease in individuals with diabetes. Use of statins and aspirin is beneficial for most patients with chronic kidney disease who are at high cardiovascular risk, although research is needed to ascertain how to best prevent cardiovascular disease in this cohort. Models of care that facilitate delivery of the many complex aspects of treatment simultaneously could enhance management, although effects on clinical outcomes need further assessment. Novel clinical methods to better identify patients at risk of progression to later stages of chronic kidney disease, including kidney failure, are needed to target management to high-risk subgroups.

Indexed as

Angiotensin-Converting Enzyme InhibitorsAngiotensin II Type 1 Receptor BlockersChronic DiseaseCreatinineDiabetic NephropathiesGlomerular Filtration RateHumansKidney DiseasesAngiotensin-Converting Enzyme InhibitorsAngiotensin II Type 1 Receptor BlockersCreatinine

Identifiers

PMID20382326
OpenAlexW2118292923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.