ArticlePsychiatry research2010
Poor sleep quality predicts onset of either major depression or subsyndromal depression with irritability during interferon-alpha treatment.
Article in Psychiatry research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07660107 (Clinical Trial of Oral Supplementation With Novel Mycolicibacterium), which is not on this map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Trial of Oral Supplementation With Novel Mycolicibacterium (KGA-10)
Who cites it
36 citing papers in PubMed, 63 citations in OpenAlex.
- Preexisting mild sleep disturbance as a vulnerability factor for inflammation-induced depressed mood: a human experimental study.Translational psychiatry · 2016Trial
- Inhibition of tumor necrosis factor improves sleep continuity in patients with treatment resistant depression and high inflammation.Brain, behavior, and immunity · 2015Trial
- Effect of 2 psychotherapies on depression and disease activity in pediatric Crohn's disease.Inflammatory bowel diseases · 2015Trial
- A randomized controlled trial of an internet intervention for adults with insomnia: effects on comorbid psychological and fatigue symptoms.Journal of clinical psychology · 2013Trial
- Associations between sleep quality and irritability: Testing the mediating role of emotion regulation.Personality and individual differences · 2023Article
- Healthy Debate: Major Depression among Older Immigrants and the United States 2016 Election.Journal of immigrant and minority health · 2022Article
- Moderators of inflammation-related depression: a prospective study of breast cancer survivors.Translational psychiatry · 2021Article
- Mental Health in Student Athletes: Associations With Sleep Duration, Sleep Quality, Insomnia, Fatigue, and Sleep Apnea Symptoms.Athletic training & sports health care · 2021Article
- Insomnia May Mediate the Relationship Between Stress and Anxiety: A Cross-Sectional Study in University Students.Nature and science of sleep · 2021Article
- Article
- Poor sleep quality and associated factors among prisoners of the Diredawa correctional facility in eastern Ethiopia.Annals of general psychiatry · 2020Article
- Insomnia mediates the longitudinal relationship between anxiety and depressive symptoms in a nationally representative sample of adolescents.Depression and anxiety · 2018Article
- Sleep disturbance and kynurenine metabolism in depression.Journal of psychosomatic research · 2017Article
- Depressive symptoms, quality of sleep, and disease control in women with asthma.Sleep & breathing = Schlaf & Atmung · 2017Article
- Sleep Health: Reciprocal Regulation of Sleep and Innate Immunity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Review
- Pathogen-Host Defense in the Evolution of Depression: Insights into Epidemiology, Genetics, Bioregional Differences and Female Preponderance.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Review
- Investigation of sedative and hypnotic effects of Amygdalus communis L. extract: behavioral assessments and EEG studies on rat.Journal of natural medicines · 2016Article
- Polyunsaturated fatty acids moderate the effect of poor sleep on depression risk.Prostaglandins, leukotrienes, and essential fatty acids · 2016Article
- Validation of the Behavioral Risk Factor Surveillance System Sleep Questions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Article
- Study of Sedative-Hypnotic Effects of Aloe vera L. Aqueous Extract through Behavioral Evaluations and EEG Recording in Rats.Iranian journal of pharmaceutical research : IJPR · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
Major depressive disorder (MDD) often occurs during pegylated IFN-alpha2 (IFN-alpha) treatment. Identifying who is at risk for MDD in this population is essential, and epidemiological studies suggest that sleep may be related to depression risk. Controlling for pre-existing depression symptoms, we therefore examined whether sleep quality prior to IFN-alpha treatment would predict subsequent MDD incidence during IFN-alpha treatment. Adults with hepatitis C but without current clinical MDD (n=86) were evaluated prior to IFN-alpha treatment and then prospectively monitored during treatment using self-report measures of sleep quality (PSQI), depression (BDI), and anger and irritability (AIAQ), as well as with Structured Clinical Interviews for DSM-IV Axis I Disorders (SCID-I). During IFN-alpha treatment, 19% developed MDD, 19% developed subsyndromal depression with irritability, and one developed mania. Controlling for baseline depression symptoms and past history of depression, patients with worse sleep quality (PSQI > or = 10) prior to treatment had a significantly shorter time until they developed MDD or any severe psychiatric problem. These findings may have important implications for understanding, predicting, and possibly preventing depression, particularly in individuals treated with IFN-alpha.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.