Evidence map›Paper›PMID 20381638›Full record

ReviewMicrobes and infection2010

Host responses to Candida albicans: Th17 cells and mucosal candidiasis.

Heather R Conti, Sarah L Gaffen

Open access · greenAbstract readReview
In one paragraph

Review in Microbes and infection, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 149 citations in OpenAlex.

  1. Review
  2. Molecular mechanisms, pathogenesis and therapeutic advances ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Competitive fungal commensalism mitigates candidiasis pathology.The Journal of experimental medicine · 2024
    Article
  11. Article
  12. Article
  13. Promising immunotherapeutic targets for treating candidiasis.Frontiers in cellular and infection microbiology · 2024
    Review
  14. Article
  15. Article
  16. Autosomal recessiveFrontiers in immunology · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Review

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Heather R ContiUniversity at Buffalo, SUNY, Department of Oral Biology, Buffalo, NY, USA.
Sarah L Gaffen
University at Buffalo, State University of New York · USUniversity of Pittsburgh · US

Funding

TRAINING PROGRAM IN PERIODONTAL DISEASEST32DE007034 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SCANNAPIECO, FRANK ANDREW · 1985 to 2008
$3.5M
Structure-Function Relationships in the IL-17 ReceptorR01AR054389 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2008 to 2012
$1.8M
Immunity to Oral CandidiasisR21DE018822 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2008 to 2009
$417k
TITANIUM ALLOYS FOR PARTIAL DENTURESR43DE007034 · NIDCR · GREENMARK, INC. · PI MARKER, BERNARD C · 1985 to 1985
–
NIAMS NIH HHS AR054389NIAMS NIH HHS R01 AR054389NIDCR NIH HHS DE007034NIDCR NIH HHS DE018822NIDCR NIH HHS R21 DE018822NIDCR NIH HHS T32 DE007034
6 · The paper itself

Abstract

Candida albicans causes mucosal and disseminated candidiasis, which represent serious problems for the rapidly expanding immunocompromised population. Until recently, Th1-mediated immunity was thought to confer the primary protection, particularly for oral candidiasis. However, emerging data indicate that the newly-defined Th17 compartment appears to play the predominant role in mucosal candidiasis.

Indexed as

Adaptive ImmunityAnimalsCandida albicansCandidiasisCell LineHost-Pathogen InteractionsHumansImmunity, InnateInterleukin-17Interleukin-22Interleukin-23InterleukinsModels, AnimalMucous MembraneT-Lymphocytes, Helper-InducerInterleukin-17Interleukin-22Interleukin-23Interleukins

Identifiers

PMID20381638
PMCPMC2892252
OpenAlexW2036619734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.