ReviewClinical oncology (Royal College of Radiologists (Great Britain))2010
Management of thyroid nodules and surgery for differentiated thyroid cancer.
Review in Clinical oncology (Royal College of Radiologists (Great Britain)), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Completion Thyroidectomy Trends and Rates: A Systematic Review and Meta-Analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025Pooled it
- Review
- Rethinking the prognosis model of differentiated thyroid carcinoma.Frontiers in endocrinology · 2024Article
- Quality of Life and Surgical Outcome of Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) versus Open Thyroid Surgery: Experience from a Single Center in Vietnam.Journal of thyroid research · 2022Article
- Health-related quality of life in long-term differentiated thyroid cancer survivors: A cross-sectional Tunisian-based study.Frontiers in endocrinology · 2022Article
- Article
- Cost-effectiveness of fine-needle aspiration cytology (FNAC) and watchful observation for incidental thyroid nodules.Journal of endocrinological investigation · 2020Article
- Ultrasonographic Features, Nodule Size, Capsular Invasion, and Lymph Node Metastasis of Solitary Papillary Carcinoma of Thyroid Isthmus.Frontiers in oncology · 2020Article
- Article
- Quality of life after thyroid surgery.Journal of endocrinological investigation · 2017Article
- Using Ultrasonography to Evaluate the Relationship between Capsular Invasion or Extracapsular Extension and Lymph Node Metastasis in Papillary Thyroid Carcinomas.Chinese medical journal · 2017Article
- The relevance of preoperative ultrasound cervical mapping in patients with thyroid cancer.Canadian journal of surgery. Journal canadien de chirurgie · 2016Article
- Correlation Between Surgical Extent and Prognosis in Node-Negative, Early-Stage Papillary Thyroid Carcinoma Originating in the Isthmus.World journal of surgery · 2016Article
- Helicobacter pylori infection is associated with the presence of thyroid nodules in the euthyroid population.PloS one · 2013Article
- Intra- and postoperative complications in 137 cases of giant thyroid gland tumor.Oncology letters · 2012Article
- Advances in surgical therapy for thyroid cancer.Nature reviews. Endocrinology · 2011Review
- Controversies in the management of papillary thyroid cancer revisited.ISRN oncology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The incidence of well-differentiated thyroid cancer has seen a worldwide increase in the last three decades. Whether this is due to a 'true increase' in incidence or simply increased detection of otherwise subclinical disease remains unclear. The treatment of thyroid cancer revolves around appropriate surgical intervention, minimising complications and the use of adjuvant therapy in select circumstances. Prognostic features and risk stratification are crucial in determining the appropriate treatment. There continues to be considerable debate in several aspects of management in these patients. Level 1 evidence is lacking, and there are limited prospective data to direct therapy, hence limiting decision-making to retrospective analyses, treatment guidelines based on expert opinion and personal philosophies. This overview focuses on the major issues associated with the investigation of thyroid nodules and the extent of surgery. As overall survival in well-differentiated thyroid cancer exceeds 95%, it is important to reduce over-treating the large majority of patients, and focus limited resources on high-risk patients who require aggressive treatment and closer attention. The onus is on the physician to avoid treatment-related complications from thyroid surgery and to offer the most efficient and cost-effective therapeutic option.
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Registered trials
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