ArticleJournal of critical care2010
Out-of-hospital characteristics and care of patients with severe sepsis: a cohort study.
Article in Journal of critical care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 67 citations in OpenAlex.
- Randomised feasibility study of prehospital recognition and antibiotics for emergency patients with sepsis (PhRASe).Scientific reports · 2021Trial
- Host Response Biomarkers for Sepsis in the Emergency Room.Critical care (London, England) · 2023Review
- Prehospital fluid therapy in patients with suspected infection: a survey of ambulance personnel's practice.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022Article
- Prehospital administration of broad-spectrum antibiotics for sepsis patients: A systematic review and meta-analysis.Health science reports · 2022Article
- Does Being Transported by Emergency Medical Services Improve Compliance with the Surviving Sepsis Bundle and Mortality Rate? A Retrospective Cohort Study.Journal of epidemiology and global health · 2020Article
- Prehospital identification of community sepsis using biomarkers of host response.Intensive care medicine · 2020Article
- Prehospital recognition and antibiotics for 999 patients with sepsis: protocol for a feasibility study.Pilot and feasibility studies · 2018Article
- Low sensitivity of qSOFA, SIRS criteria and sepsis definition to identify infected patients at risk of complication in the prehospital setting and at the emergency department triage.Scandinavian journal of trauma, resuscitation and emergency medicine · 2017Article
- Prehospital Lactate Measurement by Emergency Medical Services in Patients Meeting Sepsis Criteria.The western journal of emergency medicine · 2016Article
- Accuracy of Prehospital Intravenous Fluid Volume Measurement by Emergency Medical Services.Prehospital emergency care · 2016Observational
- EMS patients and walk-in patients presenting with severe sepsis: differences in management and outcome.Southern medical journal · 2014Article
- Prehospital intravenous access and fluid resuscitation in severe sepsis: an observational cohort study.Critical care (London, England) · 2014Observational
- [The golden hour of sepsis: initial therapy should start in the prehospital setting].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2014Review
- Epidemiology of severe sepsis.Virulence · 2014Review
- Accuracy of prehospital transport time estimation.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2014Article
- Improving risk classification of critical illness with biomarkers: a simulation study.Journal of critical care · 2013Article
- Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome.American journal of respiratory and critical care medicine · 2012Article
- Suspicion and treatment of severe sepsis. An overview of the prehospital chain of care.Scandinavian journal of trauma, resuscitation and emergency medicine · 2012Review
- Understanding of sepsis among emergency medical services: a survey study.The Journal of emergency medicine · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
purposeEarly recognition and treatment in severe sepsis improve outcomes. However, out-of-hospital patient characteristics and emergency medical services (EMS) care in severe sepsis is understudied. Our goals were to describe out-of-hospital characteristics and EMS care in patients with severe sepsis and to evaluate associations between out-of-hospital characteristics and severity of organ dysfunction in the emergency department (ED). MATERIALS AND
methodsWe performed a secondary data analysis of existing data from patients with severe sepsis transported by EMS to an academic medical center. We constructed multivariable linear regression models to determine if out-of-hospital factors are associated with serum lactate and sequential organ failure assessment (SOFA) in the ED.
resultsTwo hundred sixteen patients with severe sepsis arrived by EMS. Median serum lactate in the ED was 3.0 mmol/L (interquartile range, 2.0-5.0) and median SOFA score was 4 (interquartile range, 2-6). Sixty-three percent (135) of patients were transported by advanced life support providers and 30% (62) received intravenous fluid. Lower out-of-hospital Glasgow Coma Scale score was independently associated with elevated serum lactate (P < .01). Out-of-hospital hypotension, greater respiratory rate, and lower Glasgow Coma Scale score were associated with greater SOFA (P < .01).
conclusionsOut-of-hospital fluid resuscitation occurred in less than one third of patients with severe sepsis, and routinely measured out-of-hospital variables were associated with greater serum lactate and SOFA in the ED.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.