Evidence map›Paper›PMID 20379861›Full record

SynthesisJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2010

Quantity of viable myocardium required to improve survival with revascularization in patients with ischemic cardiomyopathy: A meta-analysis.

Yoichi Inaba, Jennifer A Chen, Steven R Bergmann

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Observational
  7. SPECT and PET in ischemic heart failure.Heart failure reviews · 2017
    Review
  8. Revascularization in ischemic heart failure with reduced left ventricular ejection fraction. The impact of complete revascularization.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2017
    Article
  9. Novel Imaging Techniques for Heart Failure.Cardiac failure review · 2016
    Article
  10. Article
  11. Review
  12. Patient-centered imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012
    Article
  13. Prometheus's heart: what lies beneath.Journal of cellular and molecular medicine · 2012
    Article
  14. Review
  15. Review
  16. Radionuclide Imaging of Viable Myocardium: Is it Underutilized?Current cardiovascular imaging reports · 2011
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yoichi InabaDivision of Cardiovascular Medicine, Oregon Health and Science University, UHN62, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. yoichiinaba@yahoo.com
Jennifer A Chen
Steven R Bergmann
Mount Sinai Beth Israel · USOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis meta-analysis was conducted to determine optimal cutoff values for the assessment of viability using various imaging techniques for which revascularization would offer a survival benefit in patients with ischemic cardiomyopathy (ICM). METHODS AND

resultsWe searched five electronic databases to identify relevant studies through December 2008. Relative risks of cardiac death, both in patients with and without viability, were calculated in each study. In order to estimate the optimal threshold for the presence of viability, we assumed a linear relationship between the amount of viable myocardium and survival benefit of revascularization. Twenty-nine studies (4,167 patients) met the inclusion criteria. The optimal threshold for the presence of viability was estimated to be 25.8% (95% CI: 16.6-35.0%) by positron emission tomography using 18F-fluorodeoxyglucose-perfusion mismatch, 35.9% (95% CI: 31.6-40.3%) by stress echocardiography using contractile reserve or ischemic responses, and 38.7% (95% CI: 27.7-49.7%) by single photon emission computed tomography using thallium-201 or technetium-99m MIBI myocardial perfusion.

conclusionsThe calculated amount of viable myocardium determined to lead to improved survival was different among imaging techniques. Thus, separate cutoff values for imaging modalities may be helpful in determining which patients with ICM benefit from revascularization.

Indexed as

CardiomyopathiesDiagnostic ImagingFemaleHumansIncidenceMaleMyocardial IschemiaMyocardial RevascularizationPrognosisReproducibility of ResultsRisk AssessmentRisk FactorsSensitivity and SpecificitySurvival AnalysisSurvival Rate

Identifiers

PMID20379861
OpenAlexW2038365509

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.