ArticleMicrobiology (Reading, England)2010
Role of bacteriocins in mediating interactions of bacterial isolates taken from cystic fibrosis patients.
Article in Microbiology (Reading, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 77 citations in OpenAlex.
- Long-term culturing ofApplied and environmental microbiology · 2025Article
- Polymicrobial infection in cystic fibrosis and future perspectives for improving Mycobacterium abscessus drug discovery.npj antimicrobials and resistance · 2024Review
- RNA-Seq reveals that Pseudomonas aeruginosa mounts growth medium-dependent competitive responses when sensing diffusible cues from Burkholderia cenocepacia.Communications biology · 2024Article
- Review
- Adaptive Interactions ofPathogens (Basel, Switzerland) · 2021Article
- Polymicrobial Interactions in the Cystic Fibrosis Airway Microbiome Impact the Antimicrobial Susceptibility ofAntibiotics (Basel, Switzerland) · 2021Review
- Proteomic Studies of the Biofilm Matrix including Outer Membrane Vesicles ofMicroorganisms · 2020Article
- Bacteriocins, Antimicrobial Peptides from Bacterial Origin: Overview of Their Biology and Their Impact against Multidrug-Resistant Bacteria.Microorganisms · 2020Review
- Quorum sensing-induced phenotypic switching as a regulatory nutritional stress response in a competitive two-species biofilm: An individual-based cellular automata model.Journal of biosciences · 2020Article
- Fostering Innovation in the Treatment of Chronic Polymicrobial Cystic Fibrosis-Associated Infections Exploring Aspartic Acid and Succinic Acid as Ciprofloxacin Adjuvants.Frontiers in cellular and infection microbiology · 2020Article
- Bacterial Community Interactions During Chronic Respiratory Disease.Frontiers in cellular and infection microbiology · 2020Review
- Life in the cystic fibrosis upper respiratory tract influences competitive ability of the opportunistic pathogenRoyal Society open science · 2018Article
- Microbial Interactions in the Cystic Fibrosis Airway.Journal of clinical microbiology · 2018Article
- CsrA and its regulators control the time-point of ColicinE2 release in Escherichia coli.Scientific reports · 2018Article
- The bacterium Pseudomonas aeruginosa senses and gradually responds to interspecific competition for iron.Evolution; international journal of organic evolution · 2018Article
- Mechanisms and Targeted Therapies for Pseudomonas aeruginosa Lung Infection.American journal of respiratory and critical care medicine · 2018Review
- The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung.FEMS microbiology letters · 2017Review
- A Broad-Host-Range Tailocin from Burkholderia cenocepacia.Applied and environmental microbiology · 2017Article
- Interference Competition Among Household Strains of Pseudomonas.Microbial ecology · 2016Article
- Metabolic modeling of a chronic wound biofilm consortium predicts spatial partitioning of bacterial species.BMC systems biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Pseudomonas aeruginosa (Pa) and Burkholderia cepacia complex (Bcc) lung infections are responsible for much of the mortality in cystic fibrosis (CF). However, little is known about the ecological interactions between these two, often co-infecting, species. This study provides what is believed to be the first report of the intra- and interspecies bacteriocin-like inhibition potential of Pa and Bcc strains recovered from CF patients. A total of 66 strains were screened, and shown to possess bacteriocin-like inhibitory activity (97 % of Pa strains and 68 % of Bcc strains showed inhibitory activity), much of which acted across species boundaries. Further phenotypic and molecular-based assays revealed that the source of this inhibition differs for the two species. In Pa, much of the inhibitory activity is due to the well-known S and RF pyocins. In contrast, Bcc inhibition is due to unknown mechanisms, although RF-like toxins were implicated in some strains. These data suggest that bacteriocin-based inhibition may play a role in governing Pa and Bcc interactions in the CF lung and may, therefore, offer a novel approach to mediating these often fatal infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.